Zhao Ze-Rui, Li Zheng, Situ Dong-Rong, Ng Calvin S H
Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China ;
Institute of Digestive Disease, Chow Yuk Ho Technology Centre for Innovative Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China ;
J Thorac Dis. 2016 Aug;8(Suppl 8):S618-26. doi: 10.21037/jtd.2016.03.93.
The concept of personalized medicine, which aims to provide patients with targeted therapies while greatly reducing surgical trauma, is gaining popularity among Asian clinicians. Single port video-assisted thoracic surgery (VATS) has rapidly gained popularity in Hong Kong for major lung resections, despite bringing new challenges such as interference between surgical instruments and insertion of the optical source through a single incision. Novel types of endocutters and thoracoscopes can help reduce the difficulties commonly encountered during single-port VATS. Our region has been the testing ground and has led the development of many of these innovations. Performing VATS, in particular single-port VATS in hybrid operating theatre helps to localise small pulmonary lesions with real-time images, thus increasing surgical accuracy and pushes the boundaries in treating subcentimeter diseases. Such approach may be assisted by use of electromagnetic navigational bronchoscopy in the same setting. In addition, sublobar resection can also be more individualised according to pathologic tumour subtype that require rapid intraoperative diagnostic test to guide appropriate surgical therapy. A focus on technology and innovation for large tumours that require chest wall resection and reconstructions have also been on going, with new materials and prostheses that may be tailored to each individual needs. The current paper reviews the literature pertaining to the above topics and discusses recent related innovations in Hong Kong, highlighting the study results and future perspectives.
个性化医疗的概念旨在为患者提供靶向治疗,同时大幅减少手术创伤,在亚洲临床医生中越来越受欢迎。单孔电视辅助胸腔镜手术(VATS)在香港已迅速普及用于主要的肺切除术,尽管它带来了一些新挑战,如手术器械之间的干扰以及通过单一切口插入光源。新型的切割器和胸腔镜有助于减少单孔VATS中常见的困难。我们所在地区一直是试验场,并引领了许多此类创新的发展。在杂交手术室进行VATS,特别是单孔VATS,有助于利用实时图像定位小的肺部病变,从而提高手术准确性,并拓展了治疗亚厘米级疾病的边界。在同一环境中使用电磁导航支气管镜可能有助于这种方法。此外,根据需要快速术中诊断测试以指导适当手术治疗的病理肿瘤亚型,肺段切除术也可以更加个体化。对于需要胸壁切除和重建的大肿瘤,对技术和创新的关注也一直在进行,有可根据个体需求定制的新材料和假体。本文回顾了与上述主题相关的文献,并讨论了香港最近的相关创新,突出了研究结果和未来展望。