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表现为孤立性恶性病变的胸壁神经鞘瘤:一例报告

Chest wall schwannoma presenting as a solitary malignant lesion: a case report.

作者信息

Galukande M, Khingi A

机构信息

International Hospital Kampala, Namuwongo, P.O. Box 8177, Kampala, Uganda ; Surgery Department, College of Health Sciences, Makerere University, Kampala, Uganda.

International Hospital Kampala, Kampala, Uganda.

出版信息

Springerplus. 2016 Sep 13;5(1):1549. doi: 10.1186/s40064-016-3270-6. eCollection 2016.

DOI:10.1186/s40064-016-3270-6
PMID:27652122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5021647/
Abstract

BACKGROUND

Chest wall schwannomas are rare tumors arising from the intercostals nerves. Schwannomas are lobulated, encapsulated spherical masses, different from neurofibromas in that matter. Men and women are equally affected in their third and fourth decades.

CASE PRESENTATION

A 42 year old female presented with a 6 month history of progressively worsening pain over the right shoulder and chest wall, aggravated by movement and with associated right arm oedema and paraesthesia. She believed mild symptoms began 2 years prior to presentation. The histopathological examination revealed a benign lesion; a schwannoma with degenerative changes. The section revealed a benign nerve sheath tumor characterized by a proliferation of band spindle cells arranged in fascicles and variable cellularity and associated with dilated and think walled blood vessels.

CONCLUSION

Chest wall schwannomas are rare; they mimic chest wall malignant lesions.

摘要

背景

胸壁神经鞘瘤是起源于肋间神经的罕见肿瘤。神经鞘瘤呈分叶状、有包膜的球形肿块,在这方面与神经纤维瘤不同。男女在第三和第四个十年受影响的几率相同。

病例报告

一名42岁女性,有6个月的右肩和胸壁疼痛逐渐加重的病史,运动时加重,并伴有右臂水肿和感觉异常。她认为轻微症状在就诊前2年就已开始。组织病理学检查显示为良性病变;一个有退行性改变的神经鞘瘤。切片显示为良性神经鞘瘤,其特征是束状排列的带状梭形细胞增殖、细胞密度可变,并伴有扩张的薄壁血管。

结论

胸壁神经鞘瘤罕见;它们酷似胸壁恶性病变。

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本文引用的文献

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Benign intercostal schwannoma mimicking a solitary metastasis from lung cancer.酷似肺癌孤立性转移灶的良性肋间神经鞘瘤
Thorax. 2010 Aug;65(8):753-4. doi: 10.1136/thx.2009.129189. Epub 2010 Jun 7.
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