Toh Yoon Ezekiel Wong, Yoneda Kaori, Nakamura Shinya, Nishihara Kazuki
Department of Internal Medicine (Gastroenterology), Hiroshima Kyoritsu Hospital, Hiroshima City, Japan.
Endocopy Center, Hiroshima Kyoritsu Hospital, Hiroshima City, Japan.
Endosc Int Open. 2016 Sep;4(9):E990-6. doi: 10.1055/s-0042-112587. Epub 2016 Aug 30.
Percutaneous endoscopic gastrostomy (PEG) using the introducer technique is not only useful in patients with upper digestive tract stenosis but has been shown to reduce peristomal infection. In this study, we evaluated the safety and utility of a novel large-caliber introducer PEG kit (using 20 Fr size tube) compared with a push kit of similar size.
One hundred and thirty-six patients who received PEG at our hospital between January 2014 and December 2015 were retrospectively analyzed. Baseline characteristics, laboratory biomarkers, hemodynamic changes, postoperative adverse events and clinical outcomes with both kits were compared.
The new introducer PEG kit was used in 61 patients while the remaining 75 patients received tube placement using a push technique PEG kit. Except for the prevalence of dementia, which was lower in the introducer PEG kit group, baseline characteristics were similar in both groups. Tube placements were 100 % successful with both PEG kits and there were no significant differences in the change of postoperative hemodynamic or laboratory biomarkers. The Introducer PEG kit group experienced fewer incidence of feeding-related aspiration pneumonia (8.2 % vs. 24 %, P = 0.02), lower peristomal infection scores (1.2 vs. 1.6, P < 0.01), shorter postoperative length of stay (16 days vs. 23.7 days, P = 0.01) and fewer deaths at day 60 (3.3 % vs. 16 %, P = 0.02).
Gastrostomy using the new large-caliber introducer PEG kit is safe and produced non-inferior (with some favourable) results when compared to the push technique using similar size tubes.
采用导入器技术的经皮内镜下胃造口术(PEG)不仅对上消化道狭窄患者有用,而且已被证明可减少造口周围感染。在本研究中,我们评估了一种新型大口径导入器PEG套件(使用20 Fr尺寸的导管)与类似尺寸的推送套件相比的安全性和实用性。
对2014年1月至2015年12月期间在我院接受PEG的136例患者进行回顾性分析。比较了两种套件的基线特征、实验室生物标志物、血流动力学变化、术后不良事件和临床结局。
61例患者使用了新型导入器PEG套件,其余75例患者使用推送技术PEG套件进行导管置入。除导入器PEG套件组痴呆患病率较低外,两组基线特征相似。两种PEG套件的导管置入成功率均为100%,术后血流动力学或实验室生物标志物变化无显著差异。导入器PEG套件组喂养相关吸入性肺炎发生率较低(8.2%对24%,P = 0.02),造口周围感染评分较低(1.2对1.6,P < 0.01),术后住院时间较短(16天对23.7天,P = 0.01),60天时死亡人数较少(3.3%对16%,P = 0.02)。
与使用类似尺寸导管的推送技术相比,使用新型大口径导入器PEG套件进行胃造口术是安全的,且产生的结果不劣(有一些有利之处)。