经皮内镜胃造口术部位转移来自头颈部鳞状细胞癌：病例系列和文献复习。
Percutaneous endoscopic gastrostomy site metastasis from head and neck squamous cell carcinoma: case series and literature review.
机构信息
Department of Otolaryngology - Head and Neck Surgery, Virginia Commonwealth University Massey Cancer Center, Richmond, VA, USA.
出版信息
J Otolaryngol Head Neck Surg. 2013 Feb 28;42(1):20. doi: 10.1186/1916-0216-42-20.
OBJECTIVES
To present our experience with head and neck squamous cell carcinoma (HNSCC) seeding of percutaneous endoscopic gastrostomy (PEG) sites and to review all reported cases to identify risk factors and develop strategies for complication avoidance.
MATERIALS AND METHODS
The records of 4 patients with PEG site metastasis from HNSCC were identified from the authors' institution. Thirty-eight further cases were reviewed following a PubMed search and evaluation of references in pertinent articles.
RESULTS
Review of 42 cases revealed the average time from PEG to diagnosis of metastatic disease to be 8 months. Average time to death from detection of PEG disease was 5.9 months. One-year survival following PEG metastasis was 35.5% with an overall mortality of 87.1%.
CONCLUSION
PEG site metastatic disease portends a poor prognosis. Early detection and aggressive therapy may provide a chance of cure. Changes in PEG technique or in timing of adjunctive therapies are possible avenues in further research to prevent this complication.
目的
介绍我们在经皮内镜胃造口术 (PEG) 部位头颈部鳞状细胞癌 (HNSCC) 播种的经验，并回顾所有报道的病例，以确定危险因素并制定避免并发症的策略。
材料和方法
从作者所在机构确定了 4 例 HNSCC 患者的 PEG 部位转移病例。通过 PubMed 搜索并评估相关文章中的参考文献，进一步回顾了 38 例病例。
结果
对 42 例病例的回顾显示，从 PEG 到诊断转移性疾病的平均时间为 8 个月。从检测到 PEG 疾病到死亡的平均时间为 5.9 个月。PEG 转移后 1 年生存率为 35.5%，总死亡率为 87.1%。
结论
PEG 部位转移疾病预后不良。早期发现和积极治疗可能有治愈的机会。改变 PEG 技术或辅助治疗的时间可能是进一步研究以预防这种并发症的途径。
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