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[结肠淋巴瘤与胆石性肠梗阻并存——病例报告]

[Coincidence of colonic lymphoma and gallstone ileus - case report].

作者信息

Černá M, Opatrný V, Nosek J, Geiger J, Třeška V, Boudová L, Buriánek V

出版信息

Rozhl Chir. 2016 Fall;95(9):377-382.

Abstract

INTRODUCTION

Primary colonic lymphoma is a very rare malignant disease of the gastrointestinal tract, accounting for 14% of all malignant diseases in this location. It is classified in the group of extranodal lymphomas; its long-term asymptomatic progression makes it different from common colorectal carcinomas making its diagnosis very difficult, more often accidental. Gallstone ileus is quite an uncommon complication of cholecystolithiasis diagnosed with difficulty. Up to 50% of cases are diagnosed during surgery. The obturated location depends on the size of the stone, location of the conjunction between the biliary and gastrointestinal tracts, and also on any preexisting stenosis due to another unknown pathology.

CASE REPORT

We present a case of an 86-year-old man treated for acute diverticulitis with typical clinical symptoms. Following further examination (colonoscopy, computed tomography) revealed a tumour-like infiltration in the sigmoid colon wall and a voluminous polyp was suspected according to the colonoscopy. Computed tomography described an obstruction by a biliary stone tumbling through the cholecystocolonic fistula. Subsequent biopsy supported the suspected malignant etiology. The patient underwent resection of the sigmoid colon sec. Hartmann; an infiltration was found in the subhepatic space, which corresponded to the described fistulisation between the biliary tract and the colon. A large 40 mm gallstone was found in the resected sigmoid colon over the stenosis and the bowel wall showed diffuse thickening with several polyps; final histopathological assessment confirmed malignant lymphoma of the plasmocytoma type. No serious complications occurred in the postoperative period; after healing, the patient was transferred to hematooncology care.

CONCLUSION

The article describes the presence of two rare diseases - colonic lymphoma and gallstone ileus. Clearly, without the biliary stone obstruction in the preexisting tumorous stenosis in the sigmoid colon, the malignant hematooncology disease would not have been diagnosed.

KEY WORDS

primary colonic lymphoma - gallstone ileus - complication of the cholecystolithiasis - extranodal lymphoma - acute diverticulitis.

摘要

引言

原发性结肠淋巴瘤是一种非常罕见的胃肠道恶性疾病,占该部位所有恶性疾病的14%。它被归类为结外淋巴瘤;其长期无症状进展使其与常见的结直肠癌不同,这使得其诊断非常困难,更多时候是偶然发现。胆石性肠梗阻是胆囊结石一种相当罕见的并发症,诊断困难。高达50%的病例在手术期间被诊断出来。梗阻部位取决于结石大小、胆道与胃肠道连接处的位置,还取决于由于其他未知病理因素导致的任何先前存在的狭窄。

病例报告

我们报告一例86岁男性,因典型临床症状接受急性憩室炎治疗。进一步检查(结肠镜检查、计算机断层扫描)后发现乙状结肠壁有肿瘤样浸润,结肠镜检查怀疑有一个巨大息肉。计算机断层扫描显示一枚胆石通过胆囊结肠瘘造成梗阻。随后的活检支持了疑似恶性病因。患者接受了乙状结肠哈特曼切除术;在肝下间隙发现浸润,这与所描述的胆道与结肠之间的瘘管形成相符。在切除的乙状结肠狭窄处发现一枚40毫米的大结石,肠壁显示弥漫性增厚并有多个息肉;最终组织病理学评估证实为浆细胞瘤型恶性淋巴瘤。术后未发生严重并发症;愈合后,患者被转至血液肿瘤学护理。

结论

本文描述了两种罕见疾病——结肠淋巴瘤和胆石性肠梗阻。显然,如果没有乙状结肠先前存在的肿瘤性狭窄中的胆石梗阻,这种恶性血液肿瘤疾病就不会被诊断出来。

关键词

原发性结肠淋巴瘤——胆石性肠梗阻——胆囊结石并发症——结外淋巴瘤——急性憩室炎

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