Drummond G B
Department of Anaesthetics, Royal Infirmary, Edinburgh.
Br J Anaesth. 1989 Jul;63(1):12-21. doi: 10.1093/bja/63.1.12.
Surface electromyograms of tongue and neck muscles were measured in 14 patients before surgery under general anaesthesia to assess their relative importance in the maintenance of airway patency during sedation with i.v. thiopentone. During the i.v. administration of successive 50-mg doses of thiopentone, the mean activity of the genioglossus, sternothyroid and sternohyoid (strap muscles), and scalene muscles decreased. There was a wide variation in response, with frequent activation of the scalene and strap muscles after small doses of thiopentone. The activity of the strap and scalene muscles changed from a tonic pattern to activity in phase with inspiration. Airway obstruction was frequent and accompanied by significant increases in phasic muscle action which did not overcome the obstruction. The pattern of changes observed suggests that loss of tonic activity in the sternothyroid and sternohyoid muscles is associated with airway obstruction.
在14例患者全身麻醉下手术前，测量其舌部和颈部肌肉的表面肌电图，以评估这些肌肉在静脉注射硫喷妥钠镇静期间维持气道通畅方面的相对重要性。在静脉连续给予50毫克硫喷妥钠剂量的过程中，颏舌肌、胸骨甲状肌和胸骨舌骨肌（带状肌）以及斜角肌的平均活动减少。反应存在很大差异，小剂量硫喷妥钠后斜角肌和带状肌频繁激活。带状肌和斜角肌的活动从紧张性模式转变为与吸气同步的活动。气道梗阻频繁发生，同时相性肌肉活动显著增加，但并未克服梗阻。观察到的变化模式表明，胸骨甲状肌和胸骨舌骨肌紧张性活动的丧失与气道梗阻有关。
