Guo Taipin, Chen Xiao, Wu Xiangnong, Shan Exian, Jin Yaju, Tai Xiantao, Liu Zili, Zhu Bowen, Yuan Kai, Chen Zukun
School of Acupuncture-Tuina and Rehabilitation, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan Province, China.
Xi'an Encephalopathy Hospital of Traditional Chinese Medicine, Xi'an, Shanxi Province, China.
Syst Rev. 2016 Sep 21;5(1):161. doi: 10.1186/s13643-016-0330-5.
Osteoporosis is a global high prevalence of chronic metabolic disease with serious disability-adjusted life years losing. Acupuncture is used to treat osteoporosis broadly in China and other countries although the evidence on effectiveness cannot give a certain answer. The aim of this systematic review protocol is to appraise the efficacy and safety of acupuncture for osteoporosis.
A literature search of randomized controlled trials focusing on acupuncture for osteoporosis will be performed in the databases of Medline, Cochrane Library, Web of Science, EBASE, Springer, WHO International Clinical Trials Registry Platform (ICTRP), China National Knowledge Infrastructure (CNKI), Wan fang, Chinese Biomedical Literature Database (CBM), Chinese Scientific Journal Database (VIP), and other possible resources with a valid search strategy. Outcomes of pain, bone mineral density, fracture, mortality, improvement proportion, biochemical indicators, quality of life, adverse event, and other valid will be extracted and merged for quantitative analysis using Review Manager software (V.5.3.5) or descriptive analysis correspondingly.
This is the first systematic review to estimate the effect of acupuncture on osteoporosis, and the result may provide evidence to clinical doctor.
PROSPERO CRD42016037829.
骨质疏松症是一种全球高发性慢性代谢疾病，导致伤残调整生命年严重损失。在中国和其他国家，针灸被广泛用于治疗骨质疏松症，尽管关于其有效性的证据尚无定论。本系统评价方案的目的是评估针灸治疗骨质疏松症的疗效和安全性。
将采用有效的检索策略，在Medline、Cochrane图书馆、科学网、EBASE、Springer、世界卫生组织国际临床试验注册平台（ICTRP）、中国知网、万方、中国生物医学文献数据库（CBM）、中文科技期刊数据库（VIP）以及其他可能的资源数据库中，检索聚焦于针灸治疗骨质疏松症的随机对照试验。将提取疼痛、骨密度、骨折、死亡率、改善比例、生化指标、生活质量、不良事件等有效结局，并相应地使用Review Manager软件（V.5.3.5）进行合并以进行定量分析，或进行描述性分析。
这是首次评估针灸对骨质疏松症疗效的系统评价，其结果可能为临床医生提供证据。
PROSPERO CRD42016037829。
