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选择性5-羟色胺再摄取抑制剂与妊娠:对母体、胎儿及新生儿风险与益处的综述

Selective serotonin reuptake inhibitors and pregnancy: A review of maternal, fetal and neonatal risks and benefits.

作者信息

Marchocki Zbigniew, Russell Noirin E, Donoghue Keelin O'

机构信息

Department of Obstetrics and Gynaecology, University College Cork, Cork University Maternity Hospital, Wilton, Cork, Ireland.

出版信息

Obstet Med. 2013 Dec;6(4):155-8. doi: 10.1177/1753495X13495194. Epub 2013 Aug 8.

Abstract

Depression is common in women of childbearing age. Whereas non-pharmacological interventions are recommended as first line interventions, pharmacological treatment may be required. Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants in pregnancy. Ideally, discussion of the risks and benefits of SSRI use in pregnancy should occur prior to pregnancy. The potential risks of psychotropic medications need to be balanced against the risks associated with untreated psychiatric conditions and the discontinuation of necessary medications.

摘要

抑郁症在育龄女性中很常见。虽然推荐非药物干预作为一线干预措施,但可能需要药物治疗。选择性5-羟色胺再摄取抑制剂(SSRI)是孕期最常用的抗抑郁药。理想情况下,应在怀孕前讨论孕期使用SSRI的风险和益处。精神药物的潜在风险需要与未治疗的精神疾病以及停用必要药物相关的风险相权衡。

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