Thatte M R, Kamdar N B, Khakkar D V, Varade M A, Thatte R L
Lokmanya Tilak Municipal General Hospital, Bombay, India.
Br J Plast Surg. 1989 Jul;42(4):405-13. doi: 10.1016/0007-1226(89)90005-2.
Experiments were performed to ascertain the perfusion and drainage of single cephalad channel saphenous venous flaps in dogs. In the first experiment a standard saphenous flap and a single cephalad channel saphenous venous island flap were dissected on contralateral thighs of dogs. A radioactive tracer, 99mTc, was injected into a foreleg vein and its appearance in both flaps was monitored with the use of a static and dynamic scanner. After this experiment, Evans blue, a vital dye, was injected into the foreleg vein of the dog. Five minutes later both flaps were excised and the dye in the flaps was assayed quantitatively. In the third experiment radioactive tracer was injected into the single cephalad channel venous flap subcutaneously and its decay in the flap as well as its uptake in the rest of the body were measured dynamically. The experiments show that the single cephalad channel venous island flap is perfused by and drains through its single cephalad vein. A mathematical model to justify the above conclusion was worked out independently, based on standard values involved in mammalian circulatory mechanisms as in dog and man.
进行实验以确定犬单头向通道隐静脉皮瓣的灌注和引流情况。在第一个实验中，在犬的对侧大腿上解剖出一个标准隐静脉皮瓣和一个单头向通道隐静脉岛状皮瓣。将放射性示踪剂99mTc注入前肢静脉，并使用静态和动态扫描仪监测其在两个皮瓣中的出现情况。在这个实验之后，将活性染料伊文思蓝注入犬的前肢静脉。五分钟后，切除两个皮瓣并对皮瓣中的染料进行定量分析。在第三个实验中，将放射性示踪剂皮下注入单头向通道静脉皮瓣，并动态测量其在皮瓣中的衰减以及在身体其他部位的摄取情况。实验表明，单头向通道静脉岛状皮瓣通过其单头向静脉进行灌注和引流。基于犬和人等哺乳动物循环机制所涉及的标准值，独立建立了一个数学模型来证明上述结论。
