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鼻内镜下泪囊鼻腔造口术对鼻窦生活质量的影响。

Impact of endoscopic dacryocystorhinostomy on sinonasal quality of life.

作者信息

Miyake Marcel M, Gregorio Luciano L, Freitag Suzanne K, Lefebvre Daniel R, Gray Stacey T, Holbrook Eric H, Bleier Benjamin S

机构信息

Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

出版信息

Am J Rhinol Allergy. 2016 Sep;30(5):189-91. doi: 10.2500/ajra.2016.30.4332.

Abstract

BACKGROUND

Dacryocystorhinostomy (DCR) is the criterion standard of surgical treatment for complete nasolacrimal obstruction and dacryocystitis. There has been an expansion in the indication of the endonasal DCR (eDCR), but the impact of surgical manipulating an otherwise healthy nasal mucosa on postoperative sinonasal quality of life remains unknown. The purpose of this study was to determine whether patients who underwent eDCR experienced any decrement in sinonasal quality of life.

METHODS

A retrospective chart review of 44 patients who underwent eDCR between June 2012 and May 2015. The primary outcome was the total and nasal-specific domain 1 scores of the disease specific validated Sino-Nasal Outcomes Test 22. Preoperative scores were compared with the postoperative scores on days 0-30, 30-90, and 90-180 visits. A subgroup analysis of patients without nasal symptoms who underwent concomitant nasal surgical procedures was also performed.

RESULTS

A statistically significant increase was observed between the preoperative score and the first postoperative score (days 0-30) in both total (7.5 [0-44] to 24 [0-51], median [interquartile range]) and domain 1 (2.5 [0-11] to 9 [0-18]) scores (p = 0.0066 and p = 0.0001, respectively). In contrast, there was no statistically significant difference between the pre- and postoperative scores on days 30-90 or 90-180. Similar results were observed in the subgroup analysis.

CONCLUSION

Analysis of our findings indicated that, in general, eDCR was well tolerated by patients and nasal symptom scores returned to baseline values within 30-90 days of surgery. The concomitant performance of septoplasty in the setting of asymptomatic septal deviation did not confer any long-term improvement in symptoms of nasal obstruction.

摘要

背景

泪囊鼻腔吻合术(DCR)是完全性鼻泪管阻塞和泪囊炎手术治疗的标准方法。鼻内镜下泪囊鼻腔吻合术(eDCR)的适应证有所扩大,但手术操作原本健康的鼻黏膜对术后鼻窦生活质量的影响尚不清楚。本研究的目的是确定接受eDCR的患者鼻窦生活质量是否有任何下降。

方法

对2012年6月至2015年5月期间接受eDCR的44例患者进行回顾性病历审查。主要结局指标是经过验证的鼻窦特异性疾病结局测试22的总分和鼻腔特定领域1得分。将术前得分与术后第0 - 30天、30 - 90天和90 - 180天就诊时的得分进行比较。还对同时进行鼻腔手术的无鼻症状患者进行了亚组分析。

结果

在总分(中位数[四分位间距]:7.5[0 - 44]至24[0 - 51])和领域1得分(2.5[0 - 11]至9[0 - 18])方面,术前得分与术后首次得分(第0 - 30天)之间均观察到统计学上的显著增加(p分别为0.0066和0.0001)。相比之下,术后第30 - 90天或90 - 180天的术前和术后得分之间无统计学显著差异。亚组分析中观察到类似结果。

结论

对我们研究结果的分析表明,总体而言,患者对eDCR耐受性良好,鼻症状评分在术后30 - 90天内恢复到基线值。在无症状鼻中隔偏曲的情况下同时进行鼻中隔成形术并未使鼻塞症状得到任何长期改善。

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