哺乳期或孕激素治疗可增强轴突切断后运动神经元的存活。
Survival of motoneurons following axotomy is enhanced by lactation or by progesterone treatment.
作者信息
Yu W H
机构信息
Department of Cell Biology and Anatomical Sciences, City University of New York Medical School, NY 10031.
出版信息
Brain Res. 1989 Jul 10;491(2):379-82. doi: 10.1016/0006-8993(89)90075-9.
PMID:2765893
Abstract
It was shown previously that neuron loss induced by nerve transection in the hypoglossal and facial motor nuclei of female rats could be reduced by long-term testosterone treatment following axotomy. In the present study, it is reported that such neuron loss could also be attenuated by lactation-related hormones and by progesterone treatment following axotomy.
摘要
先前的研究表明，雌性大鼠舌下神经和面部运动神经核因神经横断诱导的神经元损失，可通过轴突切断术后长期给予睾酮治疗而减少。在本研究中，据报道，这种神经元损失也可通过与泌乳相关的激素以及轴突切断术后给予孕酮治疗而减轻。
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