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对比剂诱导的急性肾损伤。

Contrast-Induced Acute Kidney Injury.

机构信息

Department of Internal Medicine, Division of Cardiology, Baylor University Medical Center, Dallas, Texas; Baylor Heart and Vascular Institute, Dallas, Texas; Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas; The Heart Hospital Baylor Plano, Plano, Texas.

Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.

出版信息

J Am Coll Cardiol. 2016 Sep 27;68(13):1465-1473. doi: 10.1016/j.jacc.2016.05.099.

Abstract

Coronary angiography and percutaneous intervention rely on the use of iodinated intravascular contrast for vessel and chamber imaging. Despite advancements in imaging and interventional techniques, iodinated contrast continues to pose a risk of contrast-induced acute kidney injury (CI-AKI) for a subgroup of patients at risk for this complication. There has been a consistent and graded signal of risk for associated outcomes including need for renal replacement therapy, rehospitalization, and death, according to the incidence and severity of CI-AKI. This paper reviews the epidemiology, pathophysiology, prognosis, and management of CI-AKI as it applies to the cardiac catheterization laboratory.

摘要

冠状动脉造影和经皮介入治疗依赖于碘造影剂进行血管和腔室成像。尽管影像学和介入技术不断进步,但对于存在这种并发症风险的亚组患者,碘造影剂仍然存在对比剂诱导的急性肾损伤(CI-AKI)的风险。根据 CI-AKI 的发生率和严重程度,与相关结局相关的风险信号一直是一致且分级的,包括需要肾脏替代治疗、再住院和死亡。本文回顾了 CI-AKI 的流行病学、病理生理学、预后和管理,以及其在心脏导管室的应用。

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