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幼禽胆汁和血清胆汁酸浓度及成分的变化

Changes in the concentration and composition of biliary and serum bile acids in the young domestic fowl.

作者信息

Iñarrea P, Simon M, Manzano M, Palacios J

机构信息

Department of Biochemistry and Molecular and Cellular Biology, University College of La Rioja, University of Zaragoza, Logroño, Spain.

出版信息

Br Poult Sci. 1989 Jun;30(2):353-9. doi: 10.1080/00071668908417156.

DOI:10.1080/00071668908417156
PMID:2765982
Abstract
  1. Concentrations of biliary and serum bile acids, their molecular compositions and serum cholesterol concentrations were determined in chicks at 2, 3, 4 and 6 weeks of age. 2. The concentration of biliary bile acid was maximal at 3 to 4 weeks, decreasing by 6 weeks of age. 3. The serum concentration of bile acid was maximal at three weeks of age. 4. Serum total cholesterol increased from two weeks and was maximal at 6 weeks of age. 5. Chenodeoxycholic acid was the predominant biliary unconjugated bile acid. 6. Tauro-chenodeoxycholic acid and tauro-cholic acid were the dominant molecular species of biliary and serum conjugated bile acid.
摘要
  1. 测定了2、3、4和6周龄雏鸡的胆汁和血清胆汁酸浓度、其分子组成以及血清胆固醇浓度。2. 胆汁胆汁酸浓度在3至4周时最高,到6周龄时下降。3. 胆汁酸血清浓度在3周龄时最高。4. 血清总胆固醇从2周龄开始升高,在6周龄时最高。5. 鹅去氧胆酸是主要的胆汁未结合胆汁酸。6. 牛磺鹅去氧胆酸和牛磺胆酸是胆汁和血清结合胆汁酸的主要分子种类。

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1
Changes in the concentration and composition of biliary and serum bile acids in the young domestic fowl.幼禽胆汁和血清胆汁酸浓度及成分的变化
Br Poult Sci. 1989 Jun;30(2):353-9. doi: 10.1080/00071668908417156.
2
Effects of biliary bile acid composition on biliary cholesterol saturation in gallstone patients treated with chenodeoxycholic acid and/or ursodeoxycholic acid.鹅去氧胆酸和/或熊去氧胆酸治疗的胆结石患者中胆汁胆汁酸组成对胆汁胆固醇饱和度的影响。
Gastroenterology. 1980 Dec;79(6):1192-8.
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Gastroenterology. 1982 Aug;83(2):341-7.
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Comparative effects of ursodeoxycholic acid and chenodeoxycholic acid on bile acid kinetics and biliary lipid secretion in humans. Evidence for different modes of action on bile acid synthesis.熊去氧胆酸和鹅去氧胆酸对人体胆汁酸动力学及胆汁脂质分泌的比较效应。关于胆汁酸合成不同作用模式的证据。
Gastroenterology. 1983 Dec;85(6):1248-56.
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Effect of oral chenodeoxycholic acid on bile acid kinetics and biliary lipid composition in women with cholelithiasis.口服鹅去氧胆酸对胆石症女性胆汁酸动力学和胆汁脂质成分的影响。
J Clin Invest. 1973 Nov;52(11):2809-21. doi: 10.1172/JCI107477.
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Bile acids in serum, ultrafiltrate of serum and saliva from patients with cholestatic jaundice.
Scand J Clin Lab Invest. 1987 Feb;47(1):83-9.
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Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration.熊去氧胆酸给药诱导的原发性胆汁性肝硬化患者胆汁酸组成的变化。
Hepatology. 1991 Dec;14(6):1000-7.
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Hepatology. 1997 Jun;25(6):1315-22. doi: 10.1002/hep.510250602.
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Effect of litholytic bile acids on cholesterol absorption in gallstone patients.溶石胆汁酸对胆结石患者胆固醇吸收的影响。
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