用于评估颏后缩的数字光感量表的开发与验证
Development and Validation of a Photonumeric Scale for Assessment of Chin Retrusion.
作者信息
Sykes Jonathan M, Carruthers Alastair, Hardas Bhushan, Murphy Diane K, Jones Derek, Carruthers Jean, Donofrio Lisa, Creutz Lela, Marx Ann, Dill Sara
机构信息
*Department of Otolaryngology/Facial Plastic Surgery, UC Davis Medical Group, Sacramento, California; †Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada; ‡Allergan plc, Irvine, California; §Division of Dermatology, University of California at Los Angeles, Los Angeles, California; ‖Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada; ¶Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut; #Peloton Advantage, LLC, Parsippany, New Jersey.
出版信息
Dermatol Surg. 2016 Oct;42 Suppl 1(Suppl 1):S211-S218. doi: 10.1097/DSS.0000000000000849.
BACKGROUND
A validated scale is needed for objective and reproducible comparisons of chin appearance before and after chin augmentation in practice and clinical studies.
OBJECTIVE
To describe the development and validation of the 5-point photonumeric Allergan Chin Retrusion Scale.
METHODS
The Allergan Chin Retrusion Scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each scale grade. The clinical significance of a 1-point score difference was evaluated in a review of multiple image pairs representing varying differences in severity. Interrater and intrarater reliability was evaluated in a live-subject validation study (N = 298) completed during 2 sessions occurring 3 weeks apart.
RESULTS
A difference of ≥1 point on the scale was shown to reflect a clinically meaningful difference (mean [95% confidence interval] absolute score difference, 1.07 [0.94-1.20] for clinically different image pairs and 0.51 [0.39-0.63] for not clinically different pairs). Intrarater agreement between the 2 live-subject validation sessions was substantial (mean weighted kappa = 0.79). Interrater agreement was substantial during the second rating session (0.68, primary end point).
CONCLUSION
The Allergan Chin Retrusion Scale is a validated and reliable scale for physician rating of severity of chin retrusion.
背景
在实践和临床研究中，需要一种经过验证的量表，以便对隆颏前后的颏部外观进行客观且可重复的比较。
目的
描述5分制光子数字艾尔建颏部后缩量表的开发与验证过程。
方法
艾尔建颏部后缩量表的开发内容包括一份评估指南、文字描述、变形图像以及每个量表等级的真实受试者图像。通过回顾多组代表不同严重程度差异的图像对，评估1分的分数差异的临床意义。在一项活体受试者验证研究（N = 298）中评估评分者间和评分者内信度，该研究分两次进行，间隔3周。
结果
量表上≥1分的差异被证明反映了具有临床意义的差异（临床不同图像对的平均[95%置信区间]绝对分数差异为1.07[0.94 - 1.20]，临床无差异图像对的平均绝对分数差异为0.51[0.39 - 0.63]）。两次活体受试者验证之间评分者内一致性较高（平均加权kappa = 0.79）。在第二次评分过程中评分者间一致性较高（0.68，主要终点）。
结论
艾尔建颏部后缩量表是一种经过验证且可靠的量表，用于医生对颏部后缩严重程度的评级。
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