用于评估面部皮肤纹理的数字评分量表的开发与验证
Development and Validation of a Photonumeric Scale for Evaluation of Facial Skin Texture.
作者信息
Donofrio Lisa, Carruthers Alastair, Hardas Bhushan, Murphy Diane K, Carruthers Jean, Jones Derek, Sykes Jonathan M, Creutz Lela, Marx Ann, Dill Sara
机构信息
*Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut; †Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada; ‡Allergan plc, Irvine, California; §Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada; ‖Division of Dermatology, University of California at Los Angeles, Los Angeles, California; ¶UC Davis Medical Group, Sacramento, California; #Peloton Advantage, LLC, Parsippany, New Jersey.
出版信息
Dermatol Surg. 2016 Oct;42 Suppl 1(Suppl 1):S219-S226. doi: 10.1097/DSS.0000000000000852.
BACKGROUND
A validated scale is needed for objective and reproducible comparisons of facial skin roughness before and after aesthetic treatment in practice and in clinical studies.
OBJECTIVE
To describe the development and validation of the 5-point photonumeric Allergan Skin Roughness Scale.
METHODS
The scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each grade. The clinical significance of a 1-point score difference was evaluated in a review of image pairs representing varying differences in severity. Interrater and intrarater reliability was evaluated in a live-subject validation study (N = 290) completed during 2 sessions occurring 3 weeks apart.
RESULTS
A score difference of ≥1 point was shown to reflect a clinically meaningful difference (mean [95% confidence interval] absolute score difference 1.09 [0.96-1.23] for clinically different image pairs and 0.53 [0.38-0.67] for not clinically different pairs). Intrarater agreement between the 2 validation sessions was almost perfect (weighted kappa = 0.83). Interrater agreement was almost perfect during the second rating session (0.81, primary end point).
CONCLUSION
The Allergan Skin Roughness Scale is a validated and reliable scale for physician rating of midface skin roughness.
背景
在实践和临床研究中，需要一种经过验证的量表，以便对面部皮肤粗糙度在美容治疗前后进行客观且可重复的比较。
目的
描述5分制光子数字式艾尔建皮肤粗糙度量表的开发与验证过程。
方法
该量表的开发包括一个评估指南、文字描述、变形图像以及每个等级的真实受试者图像。通过回顾代表不同严重程度差异的图像对，评估1分的分数差异的临床意义。在一项活体受试者验证研究（N = 290）中评估评分者间和评分者内的可靠性，该研究在相隔3周的两个阶段完成。
结果
≥1分的分数差异被证明反映了具有临床意义的差异（临床不同图像对的平均[95%置信区间]绝对分数差异为1.09[0.96 - 1.23]，临床无差异图像对为0.53[0.38 - 0.67]）。两次验证阶段之间的评分者内一致性几乎完美（加权kappa = 0.83）。在第二次评分阶段，评分者间一致性几乎完美（0.81，主要终点）。
结论
艾尔建皮肤粗糙度量表是一种经过验证且可靠的量表，用于医生对面中部皮肤粗糙度的评分。
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