Schmidt André, Meurer Andrea, Lenarz Katharina, Vogt Lutz, Froemel Dara, Lutz Frederick, Barker John, Stief Felix
Experimental Orthopedics and Trauma Surgery, Frankfurt Initiative for Regenerative Medicine, Johann Wolfgang Goethe University Frankfurt, Marienburgstraße 2, 60528, Frankfurt/Main, Germany.
Orthopedic University Hospital Friedrichsheim gGmbH, Marienburgstraße 2, 60528, Frankfurt/Main, Germany.
J Orthop Res. 2017 Aug;35(8):1764-1773. doi: 10.1002/jor.23444. Epub 2016 Oct 4.
In order to reduce pain caused by the affected hip joint, unilateral hip osteoarthritis patients (HOAP) adopt characteristic gait patterns. However, it is unknown if the knee and hip joint loading in the non-affected (limb ) and the affected (limb ) limb differ from healthy controls (HC) and which gait parameters correlate with potential abnormal joint loading. Instrumented 3D-gait analysis was performed on 18 HOAP and 18 sex, age, and height matched HC. The limb showed greater first and second peak external hip adduction moments (first HAM: +15%, p = 0.014; second HAM: +15%, p = 0.021, respectively), than seen in HC. In contrast, the second peak external knee adduction moment (KAM) in the limb is reduced by about 23% and 30% compared to the limb and HC, respectively. Furthermore, our patients showed characteristic gait compensation strategies including reduced peak vertical forces (pvF), a greater foot progression angle (FPA), and reduced knee range of motion (ROM) in the limb . The limb was 5.6 ± 3.8 mm shorter than the limb . Results of stepwise regression analyses showed that increased first pvF explain 16% of first HAM alterations, whereas knee ROM and FPA explain 39% of second KAM alterations. We therefore expect an increased rate of progression of OA in the hip joint of the limb and suggest that the shift in the medial-to-lateral knee joint load distribution may impact the rate of progression of OA in the limb . The level of evidence is III. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1764-1773, 2017.
为减轻患侧髋关节引起的疼痛,单侧髋关节骨关节炎患者(HOAP)会采用特定的步态模式。然而,尚不清楚未受影响(肢体)和受影响(肢体)肢体的膝关节和髋关节负荷与健康对照组(HC)是否不同,以及哪些步态参数与潜在的异常关节负荷相关。对18例HOAP患者和18例性别、年龄和身高匹配的HC进行了仪器化三维步态分析。患侧肢体的第一和第二峰值髋关节外展力矩更大(第一峰值髋关节外展力矩:增加15%,p = 0.014;第二峰值髋关节外展力矩:增加15%,p = 0.021),高于HC组。相比之下,患侧肢体的第二峰值膝关节内收力矩(KAM)与健侧肢体和HC组相比分别降低了约23%和30%。此外,我们的患者表现出特定的步态补偿策略,包括患侧肢体垂直力峰值(pvF)降低、足推进角(FPA)增大和膝关节活动范围(ROM)减小。患侧肢体比健侧肢体短5.6±3.8毫米。逐步回归分析结果表明,患侧肢体增加的第一pvF解释了第一峰值髋关节外展力矩改变的16%,而膝关节ROM和FPA解释了第二峰值膝关节内收力矩改变的39%。因此,我们预计患侧肢体髋关节骨关节炎的进展速度会加快,并认为膝关节内外侧负荷分布的改变可能会影响患侧肢体骨关节炎的进展速度。证据级别为III。©2016骨科研究协会。由Wiley Periodicals, Inc.出版。《矫形外科研究杂志》35:1764 - 1773, 2017。