Herman Lawrence, Levin Myron J, Rehm Susan
Dean and Professor, Physician Assistant Studies Gardner-Webb University, College of Health Sciences, Boiling Springs, North Carolina.
Professor of Pediatrics and Medicine, University of Colorado School of Medicine, Aurora.
Am J Med. 2016 Oct;129(10):1137. doi: 10.1016/j.amjmed.2016.08.008.
Shingles, or herpes zoster (HZ), is a common secondary infection caused by a reactivated varicella zoster virus (VZV). More than 95% of immunocompetent individuals aged at least 50 years are seropositive for VZV and are therefore at risk for developing HZ. Age-related increased incidence of HZ and its complications are thought to be related to the decline in cell-mediated immunity. Complications of HZ, which create a significant patient and economic burden, may be neurological, ophthalmological, dermatological, or visceral. HZ vaccination is essential for the prevention of HZ and its consequences. This CME activity reviews the clinical presentations and complications of HZ as well as discusses strategies for prevention (Online access: http://courses.elseviercme.com/shingles/626).
带状疱疹，即单纯疱疹病毒（HZ）感染，是由水痘-带状疱疹病毒（VZV）重新激活引起的常见继发性感染。95%以上年龄至少50岁且免疫功能正常的个体VZV血清呈阳性，因此有发生HZ的风险。HZ及其并发症的发病率随年龄增长而增加，被认为与细胞介导免疫的下降有关。HZ的并发症可累及神经、眼科、皮肤科或内脏，给患者和经济带来重大负担。HZ疫苗接种对于预防HZ及其后果至关重要。本继续医学教育活动回顾了HZ的临床表现和并发症，并讨论了预防策略（在线访问：http://courses.elseviercme.com/shingles/626）。
