Bernat Anne Laure, Lefevre Etienne, Sène Damien, Herman Philippe, Biassette Homa Adle, Froelich Sébastien
Department of Neurosurgery, Lariboisière Hospital, Paris, France; Paris-Diderot, Paris-Cité-Sorbone University, Paris, France.
Department of Neurosurgery, Lariboisière Hospital, Paris, France; Paris-Diderot, Paris-Cité-Sorbone University, Paris, France.
World Neurosurg. 2016 Dec;96:608.e13-608.e16. doi: 10.1016/j.wneu.2016.09.061. Epub 2016 Sep 23.
Granulomatosis with polyangiitis (Wegener disease) is a rare antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis that seldom involves brain and meninges. We present a case of a 35-year-old woman with granulomatosis with polyangiitis involving the brain and the meninges. The histologic diagnosis required a complete resection of the lesion. Despite the possibility of postoperative wound infection, surgery was mandatory to ascertain the diagnostic and to treat locally.
肉芽肿性多血管炎（韦格纳氏病）是一种罕见的抗中性粒细胞胞浆抗体（ANCA）阳性血管炎，很少累及脑和脑膜。我们报告一例35岁女性患肉芽肿性多血管炎累及脑和脑膜的病例。组织学诊断需要完整切除病变。尽管术后有伤口感染的可能性，但手术对于明确诊断和局部治疗是必要的。
