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新发痤疮丙酸杆菌性脓毒性关节炎。

De novo Propionibacterium acnes septic arthritis.

作者信息

Crowhurst Thomas, Tieu Joanna, Fowler Shaun, Burnet Simon

机构信息

Department of Rheumatology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Fowler Simmons Radiology, Adelaide, South Australia, Australia.

出版信息

BMJ Case Rep. 2016 Sep 26;2016:bcr2016216693. doi: 10.1136/bcr-2016-216693.

DOI:10.1136/bcr-2016-216693
PMID:27671986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5051412/
Abstract

We report the third identifiable case of septic arthritis due to Propionibacterium acnes arising in the absence of prior surgical intervention. This anaerobic Gram-positive bacillus is now recognised as an important cause of postoperative infections, typically presenting in an indolent fashion some months after surgery. Reports of de novo septic arthritis due to P. acnes are exceedingly rare. Our case adds to the literature and significantly broadens the reported pathogenic potential of the organism, which in this instance has caused rapid and serious joint destruction.

摘要

我们报告了第三例可确认的由痤疮丙酸杆菌引起的脓毒性关节炎病例,该病例在未进行过先前手术干预的情况下出现。这种厌氧革兰氏阳性杆菌现在被认为是术后感染的重要原因,通常在手术后数月以一种隐匿的方式出现。关于痤疮丙酸杆菌引起的原发性脓毒性关节炎的报道极为罕见。我们的病例丰富了文献,并显著拓宽了该生物体已报道的致病潜力,在这种情况下,它导致了快速且严重的关节破坏。

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De novo Propionibacterium acnes septic arthritis.新发痤疮丙酸杆菌性脓毒性关节炎。
BMJ Case Rep. 2016 Sep 26;2016:bcr2016216693. doi: 10.1136/bcr-2016-216693.
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Septic arthritis caused by Propionibacterium acnes.痤疮丙酸杆菌引起的化脓性关节炎。
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本文引用的文献

1
Invasive Propionibacterium acnes infections in a non-selective patient cohort: clinical manifestations, management and outcome.非选择性患者队列中的侵袭性痤疮丙酸杆菌感染:临床表现、管理及结局
Eur J Clin Microbiol Infect Dis. 2015 Mar;34(3):527-34. doi: 10.1007/s10096-014-2256-y. Epub 2014 Oct 18.
2
Bone and joint infections due to anaerobic bacteria: an analysis of 61 cases and review of the literature.厌氧菌所致骨与关节感染:61例分析及文献复习
Eur J Clin Microbiol Infect Dis. 2014 Aug;33(8):1355-64. doi: 10.1007/s10096-014-2073-3. Epub 2014 Feb 28.
3
De Novo meningitis caused by Propionibacterium acnes in a patient with metastatic melanoma.一名转移性黑色素瘤患者发生痤疮丙酸杆菌引起的新发脑膜炎。
J Clin Microbiol. 2014 Apr;52(4):1290-3. doi: 10.1128/JCM.02755-13. Epub 2014 Jan 29.
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Bacterial epidemiology of osteoarticular infections in a referent center: 10-year study.骨与关节感染的细菌流行病学:一项 10 年研究。
Orthop Traumatol Surg Res. 2013 Oct;99(6):653-8. doi: 10.1016/j.otsr.2013.02.011. Epub 2013 Aug 27.
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Propionibacterium acnes strain populations in the human skin microbiome associated with acne.痤疮丙酸杆菌株人群在人类皮肤微生物群与痤疮有关。
J Invest Dermatol. 2013 Sep;133(9):2152-60. doi: 10.1038/jid.2013.21. Epub 2013 Jan 21.
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The skin microbiome.皮肤微生物组。
Nat Rev Microbiol. 2011 Apr;9(4):244-53. doi: 10.1038/nrmicro2537.
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Postoperative joint infections due to Propionibacterium species: a case-control study.丙酸杆菌属所致的术后关节感染:一项病例对照研究。
Clin Infect Dis. 2009 Oct 1;49(7):1083-5. doi: 10.1086/605577.
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The value of synovial fluid assays in the diagnosis of joint disease: a literature survey.关节液检测在关节疾病诊断中的价值:一项文献综述。
Ann Rheum Dis. 2002 Jun;61(6):493-8. doi: 10.1136/ard.61.6.493.
9
Septic arthritis caused by Propionibacterium acnes.痤疮丙酸杆菌引起的化脓性关节炎。
JAMA. 1982 Oct 8;248(14):1740-1.
10
Infectious arthritis caused by Propionibacterium acnes: a report of two cases.痤疮丙酸杆菌引起的感染性关节炎:两例报告。
Ann Rheum Dis. 1989 Oct;48(10):851-2. doi: 10.1136/ard.48.10.851.