Clason A E, Stonebridge P A, Duncan A J, Nolan B, Jenkins A M, Ruckley C V
Vascular Surgery Unit, Royal Infirmary, Edinburgh, U.K.
Eur J Vasc Surg. 1989 Aug;3(4):339-43. doi: 10.1016/s0950-821x(89)80071-4.
A series of 204 consecutive patients with acute lower limb ischaemia was treated over a 5-year period in a Regional Vascular Unit. The mean age was 70 years, with a range of 41-98 and a female to male ratio of 1:0.94. Eighty-eight percent were treated by operation. Twenty-one had simultaneous vascular reconstructive procedures. Fifty-three patients died within 30 days (mortality rate 26%), and 12 required major amputation. Of these, four died resulting in a limb salvage rate of 95% in the survivors. An analysis of factors affecting outcome has shown increasing age, level of occlusion, recent myocardial infarction, pre-existing peripheral arterial disease and cardiopulmonary functional class to be major determinants of morbidity and mortality.
在一个地区血管病治疗中心，在5年期间内连续治疗了204例急性下肢缺血患者。平均年龄为70岁，年龄范围在41至98岁之间，女性与男性的比例为1:0.94。88%的患者接受了手术治疗。21例患者同时进行了血管重建手术。53例患者在30天内死亡（死亡率为26%），12例患者需要进行大截肢手术。其中，4例患者死亡，幸存者的肢体挽救率为95%。对影响预后因素的分析表明，年龄增长、闭塞部位、近期心肌梗死、既往存在的外周动脉疾病以及心肺功能分级是发病率和死亡率的主要决定因素。
