Alberts A S, Schulz E J, Falkson G, Simson I W, Coccia-Portugal M A
Department of Medical Oncology, University of Pretoria, South Africa.
Dermatologica. 1989;178(4):221-4. doi: 10.1159/000248432.
A patient with scleromyxoedema was treated for 6 years with cytostatic drugs. During this time the skin lesions followed a fluctuating but progressive course. After 6 years she developed Hodgkin's lymphoma of the mixed cellularity type. Intensive cytostatic treatment given for Hodgkin's disease resulted in virtually complete disappearance of the scleromyxoedema lesions. The development of Hodgkin's disease is considered fortuitous and not due to the previous cytostatic drugs.
一名硬化性黏液水肿患者接受了6年的细胞毒性药物治疗。在此期间,皮肤病变呈波动但渐进性发展。6年后,她患上了混合细胞型霍奇金淋巴瘤。针对霍奇金病进行的强化细胞毒性治疗使硬化性黏液水肿病变几乎完全消失。霍奇金病的发生被认为是偶然的,并非由于先前使用的细胞毒性药物所致。