癌胚抗原血液检测在结直肠癌复发检测中的应用。
Blood Measurement of Carcinoembryonic Antigen Level for Detecting Recurrence of Colorectal Cancer.
机构信息
University of Oxford, Oxford, England.
University of Leeds, Leeds, England.
出版信息
JAMA. 2016 Sep 27;316(12):1310-1. doi: 10.1001/jama.2016.11212.
PMID:27673308
Abstract
CLINICAL QUESTION
What is the trade-off between sensitivity and specificity at specific carcinoembryonic antigen (CEA) thresholds for detecting recurrent colorectal cancer?
BOTTOM LINE
To detect colorectal cancer recurrence, the sensitivity of CEA ranges from 68% for a threshold of 10 µg/L to 82% for a threshold of 2.5 µg/L and the specificity ranges from 97% for a threshold of 10 µg/L to 80% for a threshold of 2.5 µg/L.
摘要
临床问题
在检测复发性结直肠癌的特定癌胚抗原（CEA）阈值下，敏感性和特异性之间的权衡是什么？
关键信息
为了检测结直肠癌复发，CEA 的灵敏度范围为 10μg/L 阈值时的 68%至 2.5μg/L 阈值时的 82%，特异性范围为 10μg/L 阈值时的 97%至 2.5μg/L 阈值时的 80%。
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