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[莱姆病中的肢体与关节疼痛。一项重要的鉴别性神经学诊断]

[Limb and joint pain in Lyme disease. An important differential neurologic diagnosis].

作者信息

von Albert H H

出版信息

Fortschr Med. 1989 Aug 10;107(23):493-5.

PMID:2767602
Abstract

On the basis of 4 cases, attention is drawn to the problem of early detection of Lyme disease. The occurrence of joint pain with fluctuating spread and unresponsive to the usual antiinflammatory therapy should prompt the physician to consider lyme disease, which can be confirmed or excluded only by lumbar puncture. The CSF shows a cell count of between 300/3 and 2,000/3 cells (90% lymphocytes) and usually moderately elevated protein. A demonstration of elevated antibody titers confirms the diagnosis. The condition can be cured with antibiotics (penicillins or cephalosporins) and also cerebral nerve involvement (usual the facial nerve) with or without impairment of taste also clears up completely.

摘要

基于4个病例,提请注意莱姆病的早期检测问题。出现关节疼痛且范围波动、对常规抗炎治疗无反应,应促使医生考虑莱姆病,而莱姆病只能通过腰椎穿刺来确诊或排除。脑脊液显示细胞计数在每立方毫米300个至2000个细胞之间(90%为淋巴细胞),蛋白质通常中度升高。抗体滴度升高可确诊。该疾病可用抗生素(青霉素或头孢菌素)治愈,而且伴有或不伴有味觉障碍的脑神经受累(通常为面神经)也会完全消退。

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