Mahmoud Ahmed N, Al-Ani Mohammad, Saad Marwan, Elgendy Akram Y, Elgendy Islam Y
Division of Cardiovascular Medicine, Department of Medicine, University of Florida, Gainesville, FL, USA.
Division of Cardiovascular Medicine, Department of Medicine, University of Florida, Gainesville, FL, USA.
Heart Lung. 2016 Nov-Dec;45(6):510-514. doi: 10.1016/j.hrtlng.2016.08.009. Epub 2016 Sep 24.
Data regarding the characteristics associated with worse outcomes in Takotsubo syndrome (TTS) patients is lacking.
The National Inpatient Sample (NIS) 2012 database was utilized to calculate a risk score for in-hospital mortality following TTS that was internally and externally validated in both 2012 and 2013 databases, respectively.
The incidences of in-hospital mortality in the 2012 development sample were 0.2%, 3.2% and 15.6% in the low risk (≤2), intermediate risk (3-4) and high-risk (≥5) score groups, respectively. The risk score C-statistics were 0.86 and 0.88 in the development and external validation samples, respectively (p < 0.001). Age ≥ 80 year was associated with the highest odds ratio (OR) of mortality (OR 8.07, 95% confidence interval (CI) 5.79-11.25). Other important predictors were acute cerebrovascular accident and acute respiratory failure.
The risk of in-hospital mortality following TTS could be predicted using a simple risk score, which could aid in identifying and proper management of a higher risk group.
关于应激性心肌病（TTS）患者预后较差相关特征的数据尚缺乏。
利用2012年全国住院患者样本（NIS）数据库计算TTS患者院内死亡风险评分，并分别在2012年和2013年数据库中进行内部和外部验证。
在2012年的开发样本中，低风险（≤2）、中风险（3 - 4）和高风险（≥5）评分组的院内死亡率分别为0.2%、3.2%和15.6%。开发样本和外部验证样本的风险评分C统计量分别为0.86和0.88（p < 0.001）。年龄≥80岁与最高的死亡比值比（OR）相关（OR 8.07，95%置信区间（CI）5.79 - 11.25）。其他重要的预测因素是急性脑血管意外和急性呼吸衰竭。
可使用简单的风险评分预测TTS患者的院内死亡风险，这有助于识别和妥善管理高风险组。
