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一种用于在细胞水平研究耳蜗微力学的颞骨标本。

A temporal bone preparation for the study of cochlear micromechanics at the cellular level.

作者信息

Ulfendahl M, Flock A, Khanna S M

机构信息

Department of Physiology II, Karolinska Institute, Stockholm, Sweden.

出版信息

Hear Res. 1989 Jun 15;40(1-2):55-64. doi: 10.1016/0378-5955(89)90099-3.

Abstract

An in vitro preparation of the guinea pig temporal bone was developed for studying the micromechanical behaviour of the cochlea. The preparation consists of the cochlea opened at the apex, allowing observation of cellular structures within the cochlear partition with an optical sectioning microscope and measurements of cellular vibration with laser interferometry. The middle ear ossicles and the tympanic membrane are left intact as well as the bony part of the external auditory canal, which is used for delivering a sound stimulus to the cochlea.

摘要

为了研究耳蜗的微机械行为,开发了一种豚鼠颞骨的体外制备方法。该制备物包括在顶端打开的耳蜗,允许用光学切片显微镜观察耳蜗隔内的细胞结构,并用激光干涉测量法测量细胞振动。中耳听小骨和鼓膜以及外耳道的骨性部分保持完整,外耳道的骨性部分用于向耳蜗传递声音刺激。

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