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血液系统恶性肿瘤血小板减少症的血小板输注治疗

Platelet transfusion therapy in thrombocytopaenia of haematologic malignancies.

作者信息

Charak B S, Rao K, Parikh P M, Rawat R S, Nair C N, Advani S H

出版信息

J Assoc Physicians India. 1989 Mar;37(3):201-3.

PMID:2768161
Abstract

Thirty thrombocytopaenic patients of acute leukaemias and myelodysplastic syndrome were transfused platelets collected from ABO-matched donors using Haemonetics V30 and V50 blood processors. Twenty-seven patients had septicaemia and/or splenomegaly; 2 patients had disseminated intravascular coagulation (DIC). Pre-transfusion platelet count was 11.0 +/- 4.0 X 10(9)/L. The mean corrected count increments (CCI) 1 hour and 18 hours post-transfusion were 13.02 X 10(9)/L and 3.88 X 10(9)/L respectively, in the absence of DIC. Active bleeding stopped when platelet count was above 15.0 X 10(9)/L. There was no difference between the platelet yield from two blood processors.

摘要

30例急性白血病和骨髓增生异常综合征的血小板减少患者输注了使用Haemonetics V30和V50血液处理仪从ABO血型匹配供者采集的血小板。27例患者有败血症和/或脾肿大;2例患者有弥散性血管内凝血(DIC)。输血前血小板计数为11.0±4.0×10⁹/L。在无DIC的情况下,输血后1小时和18小时的平均校正计数增加值(CCI)分别为13.02×10⁹/L和3.88×10⁹/L。当血小板计数高于15.0×10⁹/L时,活动性出血停止。两种血液处理仪的血小板产量无差异。

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