Takashima T, Kawai K, Hirohata K, Miki A, Mizoguti H, Cooke T D
Kobe University School of Medicine, Japan.
J Bone Joint Surg Br. 1989 Aug;71(4):671-6. doi: 10.1302/0301-620X.71B4.2768320.
We studied the morphology of the haversian canals in the osteopenic cortical bone of the medial femoral neck from patients with rheumatoid arthritis and compared the findings with those in patients with osteoarthritis and with uncomplicated coxa valga. In the rheumatoid bone, the diameters of the canals were larger and many more contained osteoclasts. Fewer haversian canals showed only lining cells than in the osteoarthritic or coxa valga patients. In bone from rheumatoid patients, especially in canals with osteoclasts, small blood vessels were frequently lined by tall endothelial cells with an infiltration of mononuclear cells. These morphological differences are discussed with reference to the possible mechanisms of loss of cortical bone in rheumatoid arthritis and other conditions.
我们研究了类风湿性关节炎患者股骨内侧颈骨质疏松皮质骨中哈弗斯管的形态，并将结果与骨关节炎患者及单纯性髋外翻患者的结果进行了比较。在类风湿性骨中，哈弗斯管直径更大，且更多的哈弗斯管含有破骨细胞。与骨关节炎或髋外翻患者相比，仅显示衬里细胞的哈弗斯管更少。在类风湿性患者的骨中，尤其是在含有破骨细胞的哈弗斯管中，小血管常被高柱状内皮细胞衬里，并有单核细胞浸润。结合类风湿性关节炎及其他病症中皮质骨丢失的可能机制，对这些形态学差异进行了讨论。
