巴基斯坦拉合尔粪肠球菌介导的尿路感染患病率及其当前的抗菌药物敏感性模式。

Prevalence of Enterococcus faecalis mediated UTI and its current antimicrobial susceptibility pattern in Lahore, Pakistan.

作者信息

Hussain Abid, Sohail Muhammad, Abbas Zaigham

机构信息

Depatment of Microbiology and Molecular Genetics, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan.

出版信息

J Pak Med Assoc. 2016 Oct;66(10):1232-1236.

PMID:27686295

Abstract

OBJECTIVE

To determine the prevalence of Enterococcus faecalis and recent trends in antimicrobial sensitivity profiling.

METHODS

The study was conducted at Chughtais Lahore Lab, Lahore, Pakistan, from December 2013 to May 2014, and comprised urine specimens from suspected patients. Antimicrobial profiling of isolated strains of Enterococcus faecalis was determined by Kirby-Bauer disc-diffusion method.

RESULTS

Of the230 specimens, 161(70%) were positive for Enterococcus faecalis. The prevalence of Enterococcus faecalis-mediated urinary tract infections was 120(74.53%) in females and 41(25.46%) in males. Age-wise distribution of urinary tract infections among female patients was 41(34.16%) in >65 years age group. In males, the prevalence in the same age group was 19(46.34%). Besides, 145(90.09%) strains of Enterococcus faecalis exhibited resistance to gentamicin, 140(86.95%) to norfloxacin. Moreover, 138(85.71%) strains exhibited multi-drug resistance.

CONCLUSIONS

An overall pattern of drug resistance infections was observed in a majority of isolates.

摘要

目的

确定粪肠球菌的患病率以及抗菌药物敏感性分析的近期趋势。

方法

该研究于2013年12月至2014年5月在巴基斯坦拉合尔的Chughtais Lahore实验室进行，纳入了疑似患者的尿液标本。采用 Kirby-Bauer 纸片扩散法对分离出的粪肠球菌菌株进行抗菌谱分析。

结果

在230份标本中，161份（70%）粪肠球菌检测呈阳性。粪肠球菌介导的尿路感染患病率在女性中为120例（74.53%），在男性中为41例（25.46%）。女性患者中尿路感染按年龄分布，>65岁年龄组为41例（34.16%）。在男性中，同一年龄组的患病率为19例（46.34%）。此外，145株（90.09%）粪肠球菌菌株对庆大霉素耐药，140株（86.95%）对诺氟沙星耐药。而且，138株（85.71%）菌株表现出多重耐药性。