Denktas Ali E, Paniagua David, Jneid Hani
Baylor College of Medicine, Michael E. DeBakey VA Medical Center, 2002 Holcombe Blvd., 111B Cardiology, Houston, TX, 77030, USA.
Curr Atheroscler Rep. 2016 Oct;18(10):62. doi: 10.1007/s11883-016-0613-2.
Coronary artery disease is the most prevalent cardiovascular disease in the USA. In the majority of settings, percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD) reduces angina and improves quality of life; however, it does not improve survival and is associated with infrequent but serious complications. Selection of appropriate patients and coronary lesions for revascularization with PCI is crucial to maximize the benefit-to-risk ratio. The assessment of the hemodynamic significance of intermediate coronary lesions has been shown to improve outcomes and reduce healthcare costs. The current review summarizes the existing evidence regarding the physiological assessment of coronary lesions, with emphasis on fractional flow reserve, the most common invasive hemodynamic assessment modality.
冠状动脉疾病是美国最普遍的心血管疾病。在大多数情况下，经皮冠状动脉介入治疗（PCI）用于稳定型冠状动脉疾病（CAD）可减轻心绞痛并改善生活质量；然而，它并不能提高生存率，且会伴有不常见但严重的并发症。选择合适的患者和冠状动脉病变进行PCI血运重建对于使获益风险比最大化至关重要。已证明评估中度冠状动脉病变的血流动力学意义可改善治疗结果并降低医疗成本。本综述总结了关于冠状动脉病变生理评估的现有证据，重点是血流储备分数，这是最常见的有创血流动力学评估方式。
