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阴茎异常勃起病例报告及对这一古老病症的现代治疗方法

The Case Report of Priapus and a Modern Approach to an Ancient Affliction.

作者信息

Yücel Ömer Barış, Salabaş Emre, Ermeç Bahadır, Kadıoğlu Ateş

机构信息

Department of Urology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Department of Urology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.

出版信息

Sex Med Rev. 2017 Jan;5(1):120-128. doi: 10.1016/j.sxmr.2016.08.003. Epub 2016 Sep 26.

Abstract

INTRODUCTION

Priapism, taking its name from God Priapus, is total or partial erection lasting longer than 4 hours independent of sexual stimulus and can result in erectile dysfunction. There are three subtypes of priapism.

AIM

To review the three subtypes of priapism, their pathophysiology, current treatment options, and complications.

METHODS

The literature including priapism guidelines, review articles, and current trial studies was reviewed and the priapism type of God Priapus was investigated according to the mythology.

MAIN OUTCOME MEASURES

All three types of priapism were reviewed for etiology, diagnosis, and management. Medical and surgical treatment options were reviewed in relation to the current literature. Special emphasis concerned current treatment strategies and controversial surgical topics.

RESULTS

Ischemic priapism is the most common type, constituting 95% of all cases, and is an emergency. First-line treatments are blood aspiration and intracavernosal sympathomimetic drug injections. If these fail, then surgical shunt operations are recommended. A T-shunt combined with corporal tunneling is the currently popular option. Immediate penile prosthesis implantation is recommended for patients who present 48 to 72 hours after the onset of a priapism episode. High-flow priapism is caused by irregular arterial cavernosal blood flow, which usually occurs after a blunt perineal trauma. Antiandrogens and selective arterial embolization are the treatment options. Stuttering priapism is repetitive, self-limiting ischemic priapism and frequent in patients with sickle cell anemia. Ketoconazole is safe, cheap, and effective and appears to be a logical and suitable current treatment option to prevent further episodes, which is the primary treatment goal of stuttering priapism.

CONCLUSION

Priapism is a relatively common condition but not well known by clinicians. The lack and delay of treatment result in irreversible complications such as erectile dysfunction. Each type of priapism should be diagnosed and treated correctly with caution.

摘要

引言

阴茎异常勃起以普里阿普斯神命名,是指在无性欲刺激的情况下,阴茎完全或部分勃起持续超过4小时,可导致勃起功能障碍。阴茎异常勃起有三种亚型。

目的

回顾阴茎异常勃起的三种亚型、其病理生理学、当前的治疗选择及并发症。

方法

查阅包括阴茎异常勃起指南、综述文章及当前试验研究在内的文献,并根据神话研究普里阿普斯神型阴茎异常勃起。

主要观察指标

对所有三种类型的阴茎异常勃起进行病因、诊断及管理方面的综述。结合当前文献对药物及手术治疗选择进行综述。特别强调当前的治疗策略及有争议的手术话题。

结果

缺血性阴茎异常勃起是最常见的类型,占所有病例的95%,属于急症。一线治疗方法是血液抽吸及海绵体内注射拟交感神经药物。若这些方法无效,则建议进行手术分流手术。T形分流术结合海绵体隧道术是目前常用的选择。对于阴茎异常勃起发作后48至72小时就诊的患者,建议立即植入阴茎假体。高流量性阴茎异常勃起是由海绵体动脉血流不规则引起的,通常发生在会阴部钝性创伤后。抗雄激素药物及选择性动脉栓塞是治疗选择。间歇性阴茎异常勃起是反复出现的、自限性的缺血性阴茎异常勃起,在镰状细胞贫血患者中较为常见。酮康唑安全、价廉且有效,似乎是预防进一步发作的合理且合适的当前治疗选择,而预防进一步发作是间歇性阴茎异常勃起的主要治疗目标。

结论

阴茎异常勃起是一种相对常见的病症,但临床医生对此了解不足。治疗的缺乏及延误可导致勃起功能障碍等不可逆并发症。每种类型的阴茎异常勃起都应谨慎正确地进行诊断和治疗。

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