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子宫血管周上皮样细胞肿瘤:两例报告并文献综述

Perivascular epithelioid cell tumor of the uterus: Report of two cases and mini-review of the literature.

作者信息

Theofanakis Charalampos, Thomakos Nikolaos, Sotiropoulou Maria, Rodolakis Alexandros

机构信息

Division of Gynecologic Oncology, 1st Department of Obstetrics & Gynecology, University of Athens, Alexandra Hospital, Vasilissis Sofias 80 & Lourou 1, 11528, Athens, Greece.

Division of Gynecologic Oncology, 1st Department of Obstetrics & Gynecology, University of Athens, Alexandra Hospital, Vasilissis Sofias 80 & Lourou 1, 11528, Athens, Greece.

出版信息

Int J Surg Case Rep. 2016;28:85-87. doi: 10.1016/j.ijscr.2016.09.017. Epub 2016 Sep 24.

DOI:10.1016/j.ijscr.2016.09.017
PMID:27689526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5043388/
Abstract

INTRODUCTION

Perivascular Epithelioid Cell tumor (PEComa) is a rare neoplasm of mesenchymal origin, with the uterus being the most common site of appearance, regarding the female genital tract.

CASE REPORT

We present two cases of PEComas of the uterus in patients aged 57 and 42-years-old, presented to our department with palpable abdominal masses and abnormal vaginal bleeding. During follow up period, both patients are free of recurrent disease one and two years after surgery, respectively, without receiving any adjuvant treatment.

CONCLUSIONS

PEComa of the female gynecological tract is a rare entity presenting with variable symptoms and different prognosis for each individual case. The diagnosis is based on histopathology and immunohistochemistry reports and the optimal treatment is the surgical resection of the tumor.

摘要

引言

血管周上皮样细胞肿瘤(PEComa)是一种罕见的间叶源性肿瘤,在女性生殖道中,子宫是最常见的发病部位。

病例报告

我们报告两例子宫PEComa病例,患者分别为57岁和42岁,因可触及的腹部肿块和异常阴道出血前来我科就诊。在随访期间,两名患者分别在术后1年和2年无疾病复发,均未接受任何辅助治疗。

结论

女性生殖道PEComa是一种罕见疾病,症状多样,每个病例的预后不同。诊断基于组织病理学和免疫组化报告,最佳治疗方法是手术切除肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f99/5043388/374893c6b41a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f99/5043388/66eba070d1ed/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f99/5043388/374893c6b41a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f99/5043388/66eba070d1ed/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f99/5043388/374893c6b41a/gr2.jpg

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Am J Case Rep. 2016 May 6;17:309-14. doi: 10.12659/ajcr.896401.
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Perivascular epithelioid cell neoplasm (PEComa) of the uterus: A systematic review.子宫血管周上皮样细胞瘤(PEComa):系统评价。
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Perivascular epithelioid tumours (PEComas) of the gynaecological tract.生殖道血管周上皮样肿瘤(PEComas)
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Evidence on the neural crest origin of PEComas.关于PEComas神经嵴起源的证据。
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Laparoscopic radical excision of primary round ligament perivascular epithelioid cell tumor mimicking leiomyoma.腹腔镜下根治性切除酷似平滑肌瘤的原发性圆韧带血管周围上皮样细胞肿瘤
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Perivascular epithelioid cell neoplasms: pathology and pathogenesis.血管周上皮样细胞瘤:病理学与发病机制
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Perivascular epithelioid cell neoplasms: a systematic review of prognostic factors.血管周上皮样细胞瘤:预后因素的系统评价
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Neoplasms of the perivascular epithelioid cell involving the abdomen and the pelvis: cross-sectional imaging findings.累及腹部和盆腔的血管周上皮样细胞瘤:横断面成像表现
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HMB-45 reactivity in conventional uterine leiomyosarcomas.传统子宫平滑肌肉瘤中的HMB-45反应性。
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