Maurice P A
Schweiz Med Wochenschr. 1978 Aug 12;108(32):1238-41.
The grounds for treating or not treating chronic lymphocytic leukemias (CLL) and chronic myelocytic leukemias (CML) are discussed in the light of results in recent years. In the case of CLL, objective evaluation of treatment benefits has hitherto been difficult due to the heterogeneity of this group of diseases. A recent classification, based on hematological and clinical parameters and apparently of prognostic value, will undoubtedly help to clarify the therapeutic problem. In the case of CML, routine chemotherapy programs certainly alleviate the symptoms of the disease but have not so far achieved a significant prolongation of survival.
根据近年来的研究结果,对慢性淋巴细胞白血病(CLL)和慢性粒细胞白血病(CML)的治疗依据进行了讨论。就CLL而言,由于这类疾病的异质性,迄今为止很难对治疗效果进行客观评估。最近基于血液学和临床参数的分类,显然具有预后价值,无疑将有助于阐明治疗问题。就CML而言,常规化疗方案确实可以缓解疾病症状,但迄今为止尚未显著延长生存期。