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5%米诺地尔外用泡沫治疗男性型脱发的疗效、安全性及患者满意度

Efficacy and safety of 5% minoxidil topical foam in male pattern hair loss treatment and patient satisfaction.

作者信息

Hasanzadeh Hournaz, Nasrollahi Saman Ahmad, Halavati Nader, Saberi Maryam, Firooz Alireza

机构信息

Pharmaceutical, Cosmeceutical, and Hygienic Skin Products Clinical Evaluation Lab (DermaLab), Center for Research & Training in Skin Diseases & Leprosy (CRTSDL), Tehran University of Medical Sciences (TUMS), Tehran, Iran.

Clinical Trial Center (CTC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.

出版信息

Acta Dermatovenerol Alp Pannonica Adriat. 2016 Sep;25(3):41-44. doi: 10.15570/actaapa.2016.12.

Abstract

INTRODUCTION

Male pattern hair loss is widespread around the world. Its prevalence indicates the importance of finding the best treatment modalities. This study evaluates the efficacy and safety of minoxidil 5% topical foam in male pattern hair loss treatment and patient satisfaction.

METHODS

This study was a before-and-after trial on 17 male patients with male pattern hair loss. Subjects were instructed to apply one capful (1 ml) of minoxidil 5% topical foam on the scalp daily for 6 months. Efficacy was assessed through hair counts, subject assessment, and global photographic review.

RESULTS

Seventeen male volunteers were recruited, and three volunteers were withdrawn; 14 participated in the trial for 16 weeks, and 12 continued up to 24 weeks. The average hair count with a camera at week 16 (181.87 ± 52.42) and week 24 (194.58 ± 62.82) and with an eye count at week 16 (62.57 ± 15.28) and week 24 (69.91 ± 15.61) increased significantly compared to the baseline after intervention.

CONCLUSIONS

This study confirmed that minoxidil 5% topical foam is a safe and effective treatment for MPHL. The effect of it is evident after 24 weeks of use.

摘要

引言

男性型脱发在全球范围内广泛存在。其患病率表明寻找最佳治疗方式的重要性。本研究评估5%米诺地尔外用泡沫治疗男性型脱发的疗效、安全性及患者满意度。

方法

本研究是一项针对17名男性型脱发患者的前后对照试验。受试者被指示每天在头皮上涂抹一帽(1毫升)5%米诺地尔外用泡沫,持续6个月。通过毛发计数、受试者评估和整体照片回顾来评估疗效。

结果

招募了17名男性志愿者,3名志愿者退出;14名参与了为期16周的试验,12名持续到24周。与干预前基线相比,第16周(181.87±52.42)和第24周(194.58±62.82)相机计数的平均毛发数量以及第16周(62.57±15.28)和第24周(69.91±15.61)肉眼计数的平均毛发数量在干预后显著增加。

结论

本研究证实5%米诺地尔外用泡沫是治疗男性型雄激素性脱发的一种安全有效的疗法。使用24周后其效果明显。

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