Smylie AnneLiese, Malhotra Neel, Brassard Alain
University Dermatology Centre, 2-104 Clinical Sciences Building, Edmonton, AB T6J 2G3, Canada.
Am J Clin Dermatol. 2017 Feb;18(1):77-86. doi: 10.1007/s40257-016-0226-0.
Relapsing polychondritis, or RP, is a rare connective tissue disease characterized by relapsing-remitting destructive inflammation of the cartilaginous and other proteoglycan-rich structures in the body. Given the relatively low incidence of RP, a concise clinically relevant guide, focusing on the cutaneous manifestations of this serious disease, is lacking. In this review, we provide the dermatologist with an approach to diagnosing RP and a guide to its initial work-up, and management. We close with an overview of the currently available treatment modalities for RP.
复发性多软骨炎(RP)是一种罕见的结缔组织疾病,其特征是身体中软骨及其他富含蛋白聚糖的结构出现反复缓解的破坏性炎症。鉴于RP的发病率相对较低,目前缺乏一份聚焦于这种严重疾病皮肤表现的简明临床实用指南。在本综述中,我们为皮肤科医生提供了一种诊断RP的方法以及其初始检查和管理的指南。我们最后概述了目前可用的RP治疗方式。