低惊跳幅度可能是可卡因成瘾易感性的行为标志。
Low startle magnitude may be a behavioral marker of vulnerability to cocaine addiction.
作者信息
Wheeler Marina G, Duncan Erica, Davis Michael
机构信息
Department of Psychology, Emory University, 201 Dowman Drive, Atlanta, Georgia 30322.
Yerkes National Primate Research Center, 954 Gatewood Road, NE Atlanta, Georgia, 30329.
出版信息
Synapse. 2017 Jan;71(1):46-50. doi: 10.1002/syn.21943. Epub 2016 Nov 18.
Abstract
Cocaine addicted men have low startle magnitude persisting during prolonged abstinence. Low startle rats show greater cocaine self-administration than high startle rats. Low startle may be a marker of a vulnerability to heightened cocaine-related behaviors in rats and similarly may be a marker of vulnerability to cocaine addiction in humans.
摘要
可卡因成瘾男性在长期禁欲期间惊吓反应幅度持续较低。低惊吓反应的大鼠比高惊吓反应的大鼠表现出更强的可卡因自我给药行为。低惊吓反应可能是大鼠中对与可卡因相关行为增强的易感性的一个标志，同样也可能是人类对可卡因成瘾易感性的一个标志。
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