子宫内膜癌的免疫治疗：刻不容缓。
Immunotherapy in Endometrial Cancer: In the Nick of Time.
机构信息
Department of Medical Oncology, Institut Català d'Oncologia-IDIBELL, Barcelona, Spain.
Department of Pathology, Hospital Universitari de Bellvitge-IDIBELL, Barcelona, Spain.
出版信息
Clin Cancer Res. 2016 Dec 1;22(23):5623-5625. doi: 10.1158/1078-0432.CCR-16-1820. Epub 2016 Oct 3.
Immunotherapy with checkpoint inhibitors is changing the face of oncology treatments for many tumors, and endometrial carcinoma may not be an exception. Several endometrial cancer groups from the molecular taxonomy are characterized by having an ultramutated/hypermutated genome, which could be the first Achilles' heel identified in this malignancy in decades. Clin Cancer Res; 22(23); 5623-5. ©2016 AACRSee related article by Santin et al., p. 5682.
免疫疗法与检查点抑制剂正在改变许多肿瘤的肿瘤学治疗方法，子宫内膜癌也可能不例外。从分子分类学来看，几种子宫内膜癌群体的特点是存在超突变/高突变基因组，这可能是几十年来在这种恶性肿瘤中首次发现的致命弱点。临床癌症研究; 22(23); 5623-5. ©2016AACRSee Santin 等人的相关文章，第 5682 页。
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