颅中胚层中TWIST1调控基因的数据集以及颅中胚层与颅神经嵴的转录组比较。
Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest.
作者信息
Bildsoe Heidi, Fan Xiaochen, Wilkie Emilie E, Ashoti Ator, Jones Vanessa J, Power Melinda, Qin Jing, Wang Junwen, Tam Patrick P L, Loebel David A F
机构信息
Embryology Unit, Children's Medical Research Institute, Sydney Medical School, University of Sydney, Westmead, NSW 2145, Australia.
Bioinformatics Group, Children's Medical Research Institute, Sydney Medical School, University of Sydney, Westmead, NSW 2145, Australia.
出版信息
Data Brief. 2016 Sep 12;9:372-375. doi: 10.1016/j.dib.2016.09.001. eCollection 2016 Dec.
This article contains data related to the research article entitled "Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance" by Bildsoe et al. (2016) [1]. The data presented here are derived from: (1) a microarray-based comparison of sorted cranial mesoderm (CM) and cranial neural crest (CNC) cells from E9.5 mouse embryos; (2) comparisons of transcription profiles of head tissues from mouse embryos with a CM-specific loss-of-function of and control mouse embryos collected at E8.5 and E9.5; (3) ChIP-seq using a TWIST1-specific monoclonal antibody with chromatin extracts from TWIST1-expressing MDCK cells, a model for a TWIST1-dependent mesenchymal state.
本文包含与Bildsoe等人（2016年）[1]发表的题为“TWIST1在颅中胚层的转录靶点调节细胞-基质相互作用和间充质维持”的研究文章相关的数据。此处呈现的数据来源于：（1）对来自E9.5小鼠胚胎的分选颅中胚层（CM）和颅神经嵴（CNC）细胞进行基于微阵列的比较；（2）对E8.5和E9.5收集的具有CM特异性功能丧失的小鼠胚胎和对照小鼠胚胎的头部组织转录谱进行比较；（3）使用TWIST1特异性单克隆抗体对表达TWIST1的MDCK细胞（一种TWIST1依赖性间充质状态模型）的染色质提取物进行染色质免疫沉淀测序（ChIP-seq）。
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