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α干扰素对毛细胞白血病的治疗作用

[Therapeutic effect of interferon-alpha on hairy cell leukemia].

作者信息

Abe Y, Sakai K, Igarashi T, Ishibashi T, Shiga T, Uchida T, Kariyone S

出版信息

Rinsho Ketsueki. 1989 Apr;30(4):535-40.

PMID:2769975
Abstract

Hairy cell leukemia (HCL) is characterized by slow proliferation of special mononuclear cells. Although splenectomy has been evaluated to be the most effective traditional treatment for HCL, the response of patients to splenectomy is not necessarily satisfactory. Recently, the treatment of HCL with Interferon-alpha has been reported to be effective, and we report a female case of HCL who showed marked improvement in her hematological findings with this therapy.

摘要

毛细胞白血病(HCL)的特征是特殊单核细胞的增殖缓慢。尽管脾切除术已被评估为治疗HCL最有效的传统疗法,但患者对脾切除术的反应不一定令人满意。最近,有报道称用α干扰素治疗HCL有效,我们报告了1例HCL女性患者,经该疗法治疗后血液学检查结果有显著改善。

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