Ustinova S E, Sokolova R I, Todua F I, Kazanchian P O, Uchite'l I A
Klin Med (Mosk). 1989 May;67(5):123-7.
Unilateral adrenalectomy was performed in 32 patients with primary hyperaldosteronism due to tumour of the adrenal gland and with arterial hypertension (AH) of various degree of severity. Stable normalization of AH occurred in 14 patients and in 18 its course improved. The results of a retrospective analysis of a hypotensive effect, the morphological picture of the removed adrenal and the findings of clinico-biochemical and instrumental study made it possible to establish preoperatively the diagnostic criteria for the identification of two tumorous forms of primary hyperaldosteronism: aldosterone-producing adenoma proper and the tumorous form of adrenocortical hyperplasia. They have different pathogenesis and postadrenalectomy hypotensive effect.
对32例因肾上腺肿瘤导致原发性醛固酮增多症并伴有不同严重程度动脉高血压(AH)的患者进行了单侧肾上腺切除术。14例患者的AH实现了稳定的正常化,18例患者的病情得到改善。通过对降压效果、切除肾上腺的形态学表现以及临床生化和仪器检查结果进行回顾性分析,得以术前确立鉴别原发性醛固酮增多症两种肿瘤形式的诊断标准:真性醛固酮瘤和肾上腺皮质增生的肿瘤形式。它们具有不同的发病机制和肾上腺切除术后的降压效果。