Campara Zoran, Simic Dejan, Aleksic Predrag, Spasic Aleksandar, Milicevic Snjezana
Clinic of Urology, Military Medical Academy (MMA), Belgrade, Serbia.
Clinic of Urology, Clinical Centre of Banja Luka, Banja Luka, Bosnia and Herzegovina.
Med Arch. 2016 Jul 27;70(4):318-320. doi: 10.5455/medarh.2016.70.318-320.
Prostate carcinoma is the most frequently diagnosed carcinoma in the male population. The most typical places of the metastases are pelvic lymphatic glands, bones and lungs, and very rarely it metastasizes into a testis. The prognostic importance of testicular metastasis of prostate cancer is not yet well-known, due to a very few published cases. According to the known facts, it is certain that a metastasis of the prostate carcinoma into a testis is a sign of an advanced disease.
This work presents a 48-year-old patient, to whom an adenocarcinoma of the prostate has been proven by the pathohistological finding of transrectal biopsy, performed due to the elevated level of prostate-specific antigen (PSA). Nine years after the initial diagnosis, due to a gradual rise of PSA and tumorous enlargement of the left testis, left inguinal orchectomy and right orchectomy were performed. Metastatic dissemination of prostate adenocarcinoma into a testis was determined by a pathohistological analysis of the left testis.
The metastasis of the prostate carcinoma into a testis, as a rare localization of the metastatic dissemination, after additionally performed orchectomy along with further oncological therapy, can provide a continuation of a good life quality as well as a control of the disease in a longer time period.
前列腺癌是男性人群中最常被诊断出的癌症。转移的最典型部位是盆腔淋巴结、骨骼和肺部，很少转移至睾丸。由于已发表的病例很少，前列腺癌睾丸转移的预后重要性尚不为人所知。根据已知事实，前列腺癌转移至睾丸肯定是疾病进展的标志。
本文介绍了一名48岁患者，因前列腺特异性抗原（PSA）水平升高，经直肠活检的病理组织学检查证实患有前列腺腺癌。初次诊断9年后，由于PSA逐渐升高以及左侧睾丸肿瘤性增大，进行了左侧腹股沟睾丸切除术和右侧睾丸切除术。通过对左侧睾丸的病理组织学分析确定前列腺腺癌转移至睾丸。
前列腺癌转移至睾丸是转移扩散的罕见部位，在额外进行睾丸切除术后并结合进一步的肿瘤治疗，可以在较长时间内维持良好的生活质量并控制疾病。
