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优化活体肾移植项目:向手辅助后腹腔镜活体供肾肾切除术的转变及被动偏振三维显示系统的引入。

Optimizing a living kidney donation program: transition to hand-assisted retroperitoneoscopic living donor nephrectomy and introduction of a passive polarizing three-dimensional display system.

作者信息

Wahba Roger, Kleinert Robert, Hellmich Martin, Heiermann Nadine, Dieplinger Georg, Schlößer Hans A, Buchner Denise, Kurschat Christine, Stippel Dirk L

机构信息

Division of Transplantation Surgery, Department of General, Visceral and Cancer Surgery, Transplant Center Cologne, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.

Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany.

出版信息

Surg Endosc. 2017 Jun;31(6):2577-2585. doi: 10.1007/s00464-016-5264-4. Epub 2016 Oct 4.

DOI:10.1007/s00464-016-5264-4
PMID:27704243
Abstract

BACKGROUND

Optimizing a living kidney donation program is important to guarantee a high grade of acceptance among potential donors. Hand-assisted retroperitoneoscopic donor nephrectomy (HARP) is an alternative to the open anterior approach (AA) technique. Problems associated to the learning curve could hinder a transition. 3D display technique seems to ease minimally invasive surgery. Aim of this study was to evaluate the learning curve during the transition from AA to HARP and the influence of the 3D display system on the established technique.

METHODS

Observational study (n = 207) during transition to HARP and introduction of 3D display technique.

RESULTS

Operation time (OT), warm ischemia time (WIT) and blood loss (BL) of HARP decreased during transition. Pairwise group comparison for OT showed a significant learning effect for the first 30 out of 50 HARPs without influence on graft function. Between AA and HARP no significant difference in OT (133 ± 24 vs. 127 ± 19 min, p = 0.25) but for WIT (23 ± 28 vs. 126 ± 40 s, p < 0.005) and BL (328 ± 207 vs. 54 ± 35 ml, p < 0.005) was seen. There was neither a significant difference in donors' nor recipients' eGFR. OT (98 ± 16 vs. 106 ± 19 min, p = 0.036) and WIT (97 ± 37 vs. 120 ± 57 s, p = 0.023) were significantly shorter for the 3D technique compared to 2D.

CONCLUSION

A transition to HARP is possible without additional risk for the donor or loss of quality for the recipient. The learning curve for HARP is steep and short. The introduction of 3D display technique after transition facilitates the surgical preparation and could further help to optimize HARP.

摘要

背景

优化活体肾移植项目对于确保潜在供体的高接受度至关重要。手辅助后腹腔镜供肾切除术(HARP)是开放前路(AA)技术的一种替代方法。与学习曲线相关的问题可能会阻碍这种转变。3D显示技术似乎有助于简化微创手术。本研究的目的是评估从AA向HARP转变过程中的学习曲线以及3D显示系统对既定技术的影响。

方法

在向HARP转变并引入3D显示技术期间进行观察性研究(n = 207)。

结果

在转变过程中,HARP的手术时间(OT)、热缺血时间(WIT)和失血量(BL)均有所减少。对OT进行两两分组比较显示,在前50例HARP中的前30例存在显著的学习效应,且对移植肾功能无影响。AA与HARP之间,OT无显著差异(133±24 vs. 127±19分钟,p = 0.25),但WIT(23±28 vs. 126±40秒,p < 0.005)和BL(328±207 vs. 54±35毫升,p < 0.005)存在显著差异。供体和受体的估算肾小球滤过率(eGFR)均无显著差异。与2D技术相比,3D技术的OT(98±16 vs. 106±19分钟,p = 0.036)和WIT(97±37 vs. 120±57秒,p = 0.023)显著更短。

结论

向HARP转变对供体而言无额外风险,对受体而言也不会导致质量下降。HARP的学习曲线陡峭且短暂。转变后引入3D显示技术有助于手术准备,并可能进一步有助于优化HARP。

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Determining the Superior Technique for Living-donor Nephrectomy: the Laparoscopic Intraperitoneal Versus the Retroperitoneoscopic Approach.确定活体供肾肾切除术的最佳技术:腹腔镜经腹腔与后腹腔镜入路对比
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