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Fontan手术前后心室形态对围手术期结局影响的回顾性分析

A Retrospective Analysis of the Influence of Ventricular Morphology on the Perioperative Outcomes After Fontan Surgery.

作者信息

Kamata Mineto, Stiver Corey, Naguib Aymen, Tumin Dmitry, Tobias Joseph D

机构信息

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH.

Division of Pediatric Cardiology, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, OH.

出版信息

J Cardiothorac Vasc Anesth. 2017 Feb;31(1):128-133. doi: 10.1053/j.jvca.2016.07.024. Epub 2016 Jul 19.

Abstract

OBJECTIVES

The objectives of this study were to evaluate the effect of ventricular morphology on perioperative outcomes during Fontan surgery.

DESIGN

Retrospective cohort study.

SETTING

Single standing, not-for-profit pediatric hospital.

PARTICIPANTS

A total of 72 patients who underwent Fontan surgery using cardiopulmonary bypass without aortic cross-clamp between January 1, 2009 and December 31, 2014.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

The patients were divided into 3 categories depending on their single-ventricle lesions: (1) LV group (n = 20): left dominant and hypoplastic right ventricle; (2) RV group (n = 37): right dominant and hypoplastic left ventricle; and (3) BV group (n = 15): biventricular or indeterminate dominance. Perioperative major adverse events were collected based on the Society of Thoracic Surgeons database. The need for perioperative allogeneic blood transfusions also was determined. The mean age was 3.3±1.7 years and the mean weight was 13.6±4.0 kg. All patients had extracardiac lateral tunnel or conduit Fontan procedures. Sixty-nine of the patients (96%) underwent tracheal extubation in the operating room. Anesthesia, surgery, and CPB times were 326±68, 239±73, and 70±41 minutes, respectively. Eleven patients (15%) required allogeneic blood products intraoperatively, while 30 patients (42%) required allogeneic blood products during the perioperative period. Length of cardiac intensive care unit stay and hospital stay (median [IQR]) were 1 [1,2] and 12 [9,18] days, respectively. There was no mortality and no significant differences between groups in major postoperative complications, anesthetic or surgical variables.

CONCLUSIONS

No difference in the immediate perioperative outcomes was noted based on ventricular morphology.

摘要

目的

本研究的目的是评估心室形态对Fontan手术围手术期结局的影响。

设计

回顾性队列研究。

设置

单一的非营利性儿科医院。

参与者

2009年1月1日至2014年12月31日期间,共有72例患者在未使用主动脉夹闭的情况下接受了体外循环Fontan手术。

干预措施

无。

测量指标和主要结果

根据单心室病变情况将患者分为3类:(1)左心室组(n = 20):左心室占优势且右心室发育不全;(2)右心室组(n = 37):右心室占优势且左心室发育不全;(3)双心室组(n = 15):双心室或优势不明确。根据胸外科医师协会数据库收集围手术期主要不良事件。还确定了围手术期异体输血的需求。平均年龄为3.3±1.7岁,平均体重为13.6±4.0 kg。所有患者均接受了心外膜侧隧道或管道Fontan手术。69例患者(96%)在手术室进行了气管插管。麻醉、手术和体外循环时间分别为326±68、239±73和70±41分钟。11例患者(15%)术中需要异体血制品,而30例患者(42%)在围手术期需要异体血制品。心脏重症监护病房住院时间和住院时间(中位数[四分位间距])分别为1 [1,2]天和12 [9,18]天。无死亡病例,各组术后主要并发症、麻醉或手术变量无显著差异。

结论

基于心室形态,围手术期即刻结局无差异。

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