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常规超声在青春期异常子宫出血诊断与管理中的应用

The Utility of Routine Ultrasound in the Diagnosis and Management of Adolescents with Abnormal Uterine Bleeding.

作者信息

Pecchioli Yael, Oyewumi Lamide, Allen Lisa M, Kives Sari

机构信息

Section of Pediatric and Adolescent Gynecology, Department of Endocrinology, Hospital for Sick Children Toronto, Ontario, Canada.

Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada.

出版信息

J Pediatr Adolesc Gynecol. 2017 Apr;30(2):239-242. doi: 10.1016/j.jpag.2016.09.012. Epub 2016 Oct 6.

Abstract

STUDY OBJECTIVE

Despite the fact that most cases of abnormal uterine bleeding (AUB) in adolescence are due to an immature hypothalamic-pituitary-ovarian (HPO) axis, the current approach to investigating adolescents who present with AUB often includes pelvic ultrasound to exclude rare structural causes. The aim of this study was to determine whether an ultrasound ordered for the investigation of AUB in adolescents detects any significant anatomic pathology or alters diagnosis and management.

DESIGN, SETTING, PARTICIPANTS, AND INTERVENTIONS: A retrospective chart review of 230 patients younger than 18 years of age who presented with AUB to the gynecology clinic at the Hospital for Sick Children in Toronto, Canada between January 2010 and December 2012 was completed.

MAIN OUTCOME MEASURES

Findings on pelvic ultrasound and any further imaging as well as management choices for these patients were examined.

RESULTS

Of all patients, 67.8% (156/230) had ultrasound done as part of their AUB workup. The most common diagnosis for the patients who received ultrasound examinations and the patients who did not was AUB due to an immature HPO axis. Of the patients who received an ultrasound examination, 72.4% (113/156) had normal findings; incidental findings were identified in 17.9% (28/156) and polycystic ovary syndrome morphology in 6.4% (10/156). Structural causes of AUB were found in only 2 (1.3%) of the adolescents imaged. No patient had a change in her AUB management plan because of ultrasound findings.

CONCLUSION

Our results strongly suggest that pelvic ultrasound examination is not required in the initial investigation of AUB in the adolescent population because it did not alter treatment in any of our patients.

摘要

研究目的

尽管青春期异常子宫出血(AUB)的大多数病例是由于下丘脑 - 垂体 - 卵巢(HPO)轴不成熟所致,但目前对出现AUB的青少年进行调查的方法通常包括盆腔超声检查,以排除罕见的结构原因。本研究的目的是确定为调查青少年AUB而进行的超声检查是否能检测到任何重大的解剖病理学异常,或改变诊断和治疗方案。

设计、地点、参与者和干预措施:完成了一项对230名年龄小于18岁患者的回顾性病历审查,这些患者于2010年1月至2012年12月期间在加拿大多伦多病童医院的妇科门诊出现AUB症状。

主要观察指标

检查盆腔超声检查结果、任何进一步的影像学检查结果以及这些患者的治疗选择。

结果

在所有患者中,67.8%(156/230)进行了超声检查作为其AUB检查的一部分。接受超声检查的患者和未接受超声检查的患者最常见的诊断都是由于HPO轴不成熟导致的AUB。在接受超声检查的患者中,72.4%(113/156)检查结果正常;17.9%(28/156)发现了偶然的异常,6.4%(10/156)发现有多囊卵巢综合征形态。在接受成像检查的青少年中,仅2例(1.3%)发现了AUB的结构原因。没有患者因为超声检查结果而改变其AUB治疗方案。

结论

我们的结果强烈表明,在青少年人群AUB的初始调查中不需要进行盆腔超声检查,因为它没有改变我们任何患者的治疗方案。

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