Krishnamoorthy Venkatesh, Gowda Kiran Krishne, Rao Raman Narayana
Department of Urology, NU Hospitals, Bengaluru, Karnataka, India.
Department of Laboratory Medicine, NU Hospitals, Bengaluru, Karnataka, India.
Indian J Pathol Microbiol. 2016 Oct-Dec;59(4):507-509. doi: 10.4103/0377-4929.191805.
Renal cell carcinoma with rhabdoid differentiation (RCC-R) has an aggressive biologic behavior and poor prognosis. A recent consensus statement of the International Society of Urological Pathology (ISUP) proposed a nucleolar grading system (ISUP grade) for RCC to replace Fuhrman system and recommended reporting the presence of rhabdoid differentiation and considering tumors with rhabdoid differentiation to be ISUP Grade 4. We report a case of incidentally detected clear cell RCC-R in a 52-year-old man. This is one of the earliest cases of RCC-R (pT1b) detected and first such case from Indian subcontinent.
具有横纹肌样分化的肾细胞癌（RCC-R）具有侵袭性生物学行为且预后较差。国际泌尿病理学会（ISUP）最近的一份共识声明提出了一种用于肾细胞癌的核仁分级系统（ISUP分级）以取代福尔曼系统，并建议报告横纹肌样分化的存在情况，并将具有横纹肌样分化的肿瘤视为ISUP 4级。我们报告了一例52岁男性偶然发现的透明细胞RCC-R病例。这是最早检测到的RCC-R（pT1b）病例之一，也是印度次大陆的首例此类病例。
