National Clinical Research Center for Mental Disorders & Beijing Anding Hospital, Capital Medical University, China.
National Clinical Research Center for Mental Disorders & Beijing Anding Hospital, Capital Medical University, China; Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Psychiatry Res. 2016 Dec 30;246:246-249. doi: 10.1016/j.psychres.2016.09.046. Epub 2016 Sep 28.
Little is known about the pattern of electroconvulsive therapy (ECT) use in the clinical population in China. This study examined the percentage of ECT use and its association with clinical characteristics and quality of life (QOL) in a psychiatric center in China that caters for a population of 20 million. A total sample of 1364 inpatients was consecutively recruited for the study. Demographic and clinical data including the use of ECT were collected. Psychopathology, activity of daily living and QOL were measured using standardized instruments. The percentage of ECT use was 52.1% in the whole sample; 53.4% in major depression, 57.8% in bipolar disorder, 57.0% in schizophrenia and 32.4% in other diagnoses. There was no significant difference between the ECT and non-ECT groups in any domain of QOL. Multivariate analyses revealed that ECT was independently associated with the diagnoses of major depression, bipolar disorder and schizophrenia, physical restraint, severe aggression, better activity of daily living skills, more frequent use of antipsychotics and less frequent use of benzodiazepines. The percentage of ECT use was much greater in a major psychiatric center in China than those reported from other parts of the world. Use of ECT had no influence on the short-term QOL. Further investigations are warranted to explore the reasons for the high percentage of ECT use.
在中国,人们对电抽搐疗法(ECT)在临床人群中的应用模式知之甚少。本研究在中国的一家精神病中心调查了 ECT 的使用比例及其与临床特征和生活质量(QOL)的关系,该中心服务于 2000 万人口。本研究连续招募了 1364 名住院患者作为研究对象。收集了人口统计学和临床数据,包括 ECT 的使用情况。使用标准化工具测量了精神病理学、日常生活活动和生活质量。整个样本中 ECT 的使用率为 52.1%;在重度抑郁症中为 53.4%,在双相情感障碍中为 57.8%,在精神分裂症中为 57.0%,在其他诊断中为 32.4%。ECT 组和非 ECT 组在任何 QOL 领域均无显著差异。多变量分析显示,ECT 与重度抑郁症、双相情感障碍和精神分裂症、躯体束缚、严重攻击行为、日常生活活动技能较好、抗精神病药物使用更频繁以及苯二氮䓬类药物使用更不频繁有关。中国一家主要精神病中心的 ECT 使用率远高于世界其他地区报告的 ECT 使用率。ECT 对短期 QOL 没有影响。需要进一步调查以探讨 ECT 使用比例高的原因。