中国精神分裂症患者的电休克治疗：一项全国性调查。

Electroconvulsive Therapy in Schizophrenia in China: A National Survey.

作者信息

Li Qian, Su Yun-Ai, Xiang Yu-Tao, Shu Liang, Yu Xin, Ungvari Gabor S, Seiner Stephen J, Chiu Helen F K, Ning Yu-Ping, Wang Gao-Hua, Zhang Ke-Rang, Li Tao, Sun Li-Zhong, Shi Jian-Guo, Chen Xian-Sheng, Mei Qi-Yi, Li Ke-Qing, Si Tian-Mei

机构信息

From the *Peking University Institute of Mental Health (the Sixth Hospital) & National Clinical Research Center for Mental Disorders & the Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing; †The National Clinical Research Center for Mental Disorders & Center of Depression, Beijing Institute for Brain Disorders & Beijing Anding Hospital, Capital Medical University, Beijing; ‡Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China; §The University of Notre Dame Australia/Marian Centre, Perth; ∥School of Psychiatry & Clinical Neuroscience, University of Western Australia, Perth, Australia ¶Psychiatric Neurotherapeutics Program, McLean Hospital, Belmont & Department of Psychiatry, Harvard Medical School, Boston, MA; #Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR; **Psychiatric Hospital, Guangzhou; ††Department of Psychiatry, Renmin Hospital, Wuhan University, Wuhan; ‡‡The First Hospital of Shanxi Medical University, Shanxi Province; §§West China Hospital, Sichuan University; ∥∥Neuropsychiatric Hospital, Jilin; ¶¶Mental Health Center, Xi-an; ##Jiangxi Psychiatric Hospital, Jiangxi; ***Suzhou Guangji Hospital, Suzhou; and †††Hebei Mental Health Center, Hebei, China.

出版信息

J ECT. 2017 Jun;33(2):138-142. doi: 10.1097/YCT.0000000000000361.

DOI:10.1097/YCT.0000000000000361

PMID:27753759

Abstract

OBJECTIVE

Little is known about electroconvulsive therapy (ECT) use in the treatment of schizophrenia in China. This study examined the frequency of ECT use, its trend between 2006 and 2012, and its independent demographic and clinical correlates in a nationwide survey in China.

METHODS

A total of 5162 inpatients in 45 Chinese psychiatric hospitals/centers were interviewed (2696 in 2006 and 2466 in 2012). Patients' sociodemographic and clinical characteristics were recorded using a standardized protocol and data collection procedure.

RESULTS

Electroconvulsive therapy was used in 6.1% of the whole sample; 4.7% in 2006 and 7.7% in 2012 (P < 0.001) with wide interprovince variations. Multiple logistic regression analyses of the whole sample revealed that patients receiving ECT were more likely to be women, receive second-generation antipsychotics, treated in tertiary referral centers (level III hospitals), had a shorter illness duration, and more positive and depressive symptoms (R = 0.181; P < 0.001).

CONCLUSIONS

Electroconvulsive therapy for schizophrenia has increased between 2006 and 2012 in China. Its percentage was higher than the figures reported in most other countries. Reasons for the substantial variations in the frequency of ECT across different provinces in China require further investigations.

摘要

目的

在中国，关于电休克治疗（ECT）用于治疗精神分裂症的情况鲜为人知。本研究通过一项全国性调查，考察了ECT的使用频率、2006年至2012年间的使用趋势以及其独立的人口统计学和临床相关因素。

方法

对中国45家精神病医院/中心的5162名住院患者进行了访谈（2006年2696名，2012年2466名）。使用标准化方案和数据收集程序记录患者的社会人口学和临床特征。

结果

整个样本中6.1%的患者使用了ECT；2006年为4.7%，2012年为7.7%（P<0.001），各省之间差异很大。对整个样本进行的多因素逻辑回归分析显示，接受ECT治疗的患者更可能为女性，使用第二代抗精神病药物，在三级转诊中心（三级医院）接受治疗，病程较短，且有更多的阳性和抑郁症状（R=0.181；P<0.001）。