放射增敏作用的化学方面。敏化剂与核酸成分水溶液辐射分解产生的自由基的反应。
Chemical aspects of radiosensitization. Reaction of sensitizers with radicals produced in the radiolysis of aqueous solutions of nucleic acid components.
作者信息
Asmus K D, Deeble D J, Garner A, Ali K M, Scholes G
出版信息
Br J Cancer Suppl. 1978 Jun;3:46-9.
Abstract
The effects of oxidants (sensitizers) in the radiolysis of aqueous solutions of pyrimidine and purine bases have been investigated. Their influence on the nature of the permanent radiolysis products and on the kinetics of disappearance of transient intermediates is reported. Particular attention has been paid to the chemical fates of carbocationic intermediates which can be produced from radical-sensitizer interaction.
摘要
已对嘧啶和嘌呤碱水溶液辐射分解中氧化剂（敏化剂）的作用进行了研究。报告了它们对永久性辐射分解产物性质以及瞬态中间体消失动力学的影响。特别关注了可由自由基 - 敏化剂相互作用产生的碳正离子中间体的化学归宿。
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