Shin Kyungmin, Caudle Abigail S, Kuerer Henry M, Santiago Lumarie, Candelaria Rosalind P, Dogan Basak, Leung Jessica, Krishnamurthy Savitri, Yang Wei
1 Department of Diagnostic Radiology, Breast Imaging, The University of Texas MD Anderson Cancer Center, CPB5.3200, Unit 1350, 1515 Holcombe Blvd, Houston, TX 77030.
2 Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
AJR Am J Roentgenol. 2016 Dec;207(6):1372-1379. doi: 10.2214/AJR.16.16545. Epub 2016 Oct 11.
The purpose of this article is to describe the feasibility and safety of a multidisciplinary approach to imaging-guided axillary staging that facilitates personalized, less invasive surgical management of the axilla through targeted axillary dissection in patients with biopsy-proven nodal metastasis undergoing neoadjuvant chemotherapy.
Axillary nodal status, critical in breast cancer staging, affects prognosis and treatment. As the paradigm shifts toward minimally invasive therapy, a clip marker is placed in the biopsied metastatic node for patients with N1-N2 disease undergoing neoadjuvant chemotherapy to facilitate targeted axillary dissection of the clipped node. This node is typically localized with a radioactive seed at sentinel lymph node dissection to determine whether further axillary surgery is warranted.
本文旨在描述多学科影像引导腋窝分期方法的可行性和安全性，该方法通过对经活检证实有淋巴结转移且正在接受新辅助化疗的患者进行靶向腋窝清扫，促进对腋窝进行个性化、微创的手术管理。
腋窝淋巴结状态在乳腺癌分期中至关重要，影响预后和治疗。随着治疗模式向微创治疗转变，对于接受新辅助化疗的N1-N2期疾病患者，在活检的转移淋巴结中放置夹子标记物，以利于对夹闭的淋巴结进行靶向腋窝清扫。在哨淋巴结清扫时，该淋巴结通常用放射性种子定位，以确定是否需要进一步的腋窝手术。
