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威廉·布格·利什曼:寄生虫学家兼政治家。

William Boog Leishman: parasitologist and politician.

作者信息

Vincent H M

机构信息

Institute of Infection,Immunity and Inflammation,College of Medical,Veterinary and Life Sciences,University of Glasgow,Sir Graeme Davies Building , 120, University Place , Glasgow G12 8TA,UK.

出版信息

Parasitology. 2017 Oct;144(12):1582-1589. doi: 10.1017/S0031182016001657. Epub 2016 Oct 12.

Abstract

Famous for the discovery of the parasite, Leishmania, named after him, and the invention of Leishman's stain, William Boog Leishman should perhaps be better known for his work in military and public health, particularly the prevention of typhoid. Leishman was a Medical Officer in the British Army from 1887 until his death in 1926. His early research was on diseases affecting troops posted to stations within the British Empire. He saw cases of Leishmaniasis while stationed in India, and was able to identify the causative organism from his detailed records of his observations. Leishman's most important contribution to public health, however, was his work with typhoid, a major cause of morbidity and mortality in the army. Leishman planned experiments and the collection of data to demonstrate the efficacy of anti-typhoid inoculation and, using his considerable political skills, advocated the adoption of the vaccine. He planned for the inoculation of troops in an emergency so, when war broke out in 1914, the vaccine was available to save thousands of lives. Leishman's colleagues and mentors included Ronald Ross and Almroth Wright. Leishman was less outspoken than either Ross or Wright; this paper shows how the different contributions of the three men overlapped.

摘要

威廉·布格·利什曼因发现以他命名的寄生虫利什曼原虫以及发明利什曼染色法而闻名,但或许他在军事和公共卫生领域,尤其是在伤寒预防方面的工作更值得人们铭记。从1887年到1926年去世,利什曼一直是英国军队的一名军医。他早期的研究是关于影响驻扎在大英帝国各驻地部队的疾病。他在印度服役时见过利什曼病的病例,并能够从他详细的观察记录中识别出致病生物体。然而,利什曼对公共卫生最重要的贡献是他在伤寒方面的工作,伤寒是军队中发病和死亡的主要原因。利什曼策划实验并收集数据以证明抗伤寒接种的有效性,并且凭借他卓越的政治技巧,倡导采用这种疫苗。他还计划在紧急情况下为部队接种疫苗,所以在1914年战争爆发时,这种疫苗得以挽救了数千人的生命。利什曼的同事和导师包括罗纳德·罗斯和阿尔姆罗思·赖特。利什曼不像罗斯或赖特那样直言不讳;本文展示了这三人不同的贡献是如何相互重叠的。

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