Jayanthi R, Rajan P Boopathi
Professor.
Post Graduate, Dept. of Medicine, Govt. Stanley Medical College, Chennai, Tamil Nadu.
J Assoc Physicians India. 2016 Mar;64(3):87.
Gingival overgrowth is a common feature of periodontal diseases. Rarely it occurs as an unwanted side effect of drugs such as anticonvulsants mainly phenytoin, immunosuppressants like cyclosporine and calcium channel blockers particularly nifedipine. Among calcium channel blockers, nifedipine causes gingival overgrowth in 10% of patients whereas amlodipine-induced gingival overgrowth is very limited. Here we report four cases in hypertensives on amlodipine.
牙龈增生是牙周疾病的常见特征。它很少作为药物的不良副作用出现，如抗惊厥药（主要是苯妥英）、免疫抑制剂（如环孢素）和钙通道阻滞剂（特别是硝苯地平）。在钙通道阻滞剂中，硝苯地平会使10%的患者出现牙龈增生，而氨氯地平引起的牙龈增生则非常有限。在此，我们报告4例服用氨氯地平的高血压患者的病例。
